Twenty years of tuberculosis-driven selection shaped the evolution of the meerkat major histocompatibility complex
Fijarczyk, A. & Babik, W. Detecting balancing selection in genomes: limits and prospects. Mol. Ecol. 24, 3529–3545 (2015).…
NAD+-dependent Sirt6 is a key regulator involved in telomere shortening of in vitro-cultured preimplantation embryos
Telomere shortening, DNA damage and elevated oxidative stress in blastocysts cultured in vitro Figure 1a depicts the morphology of…
Targeting STING to disrupt macrophage-mediated adhesion in encapsulating peritoneal sclerosis
Establishing a mouse model of EPS with rapid intra-abdominal adhesions We aimed to develop a novel and more…
Targeting MondoA–TXNIP restores antitumour immunity in lactic-acid-induced immunosuppressive microenvironment
Fischer, K. et al. Inhibitory effect of tumor cell-derived lactic acid on human T cells. Blood 109, 3812–3819…
d-cysteine impairs tumour growth by inhibiting cysteine desulfurase NFS1
Cell culture Human lung adenocarcinoma A549 cells (American Type Culture Collection (ATCC) CCL-185, gift from the lab of…