Alzheimer’s decline slows with just a few thousand steps a day
Cognition deteriorates less rapidly in people with Alzheimer’s disease who take at least 3,000 to 5,000 steps per…
Disconnecting part of the brain sends it into a deep sleep
Surgically severing part of the brain can send the area into a deep sleep.Credit: Peter Cade/Getty Slow, sleep-like…
Vamp8 modulates cerebral ischemia-reperfusion injury via the autophagy-lysosome pathway
Data download The rat cerebral ischemia-reperfusion injury(CIRI) data were downloaded from the GEO database (https://www.ncbi.nlm.nih.gov/geo/) using the R…
Neural correlates of peripartum depression: a systematic review, meta-analysis and comparison to major depressive disorder
American Psychiatric Association. Diagnostic and statistical manual of mental disorders, Fifth Edition. Arlington, VA: American Psychiatric Publishing, Inc;…
Cell membrane cholesterol affects serotonin transporter efflux due to altered transporter oligomerization
Material [3H]5-HT (43.1 µCI mmol−1), [3H]dopamine (51.4 µCI mmol−1), [3H]nisoxetine (46.0 µCI mmol−1), [3H]WIN35428 (CFT) (82.6 µCI mmol−1), and Ultima GoldTM XR…
Noncontrast CT-based deep learning for predicting intracerebral hemorrhage expansion incorporating growth of intraventricular hemorrhage
In this study, we developed 2D/3D CNN models based on NCCT images to predict high-risk rHE in ICH…
Cannabis Linked to Reduced Insomnia and Anxiety
Summary: A new study suggests cannabis-based medical products may help people with insomnia sleep better over the long…
Stepwise approach to alzheimer’s disease diagnosis in primary care using cognitive screening, risk factors, neuroimaging and plasma biomarkers
Study design and population This cross-sectional, observational study was based on data from the STOP ALZHEIMER – DEBA…
Short- and long-term modulation of rat prefrontal cortical activity following single doses of psilocybin
Psilocybin induces emergence of high-frequency oscillations in infralimbic cortical LFP We chronically implanted Neuropixels probes to record neural…
Co-administration of low-dose-Naltrexone and Carbamazepine remarkedly ameliorate allodynia and cognitive deficit in a rat model of trigeminal neuralgia
Chronic TN heightens the risk of mental health conditions and can lead to reductions in the quality of…
Clinical characteristics of hypertrophic olivary degeneration following brainstem or cerebellar hemorrhage
Hypertrophic Olivary Degeneration (HOD) is a form of transsynaptic degeneration caused by lesions in the dentato-rubro-olivary pathway. It…
Predictive value of subgenual cingulate normative connectivity to TMS treatment site for antidepressant response in routine clinical practice: a prospective, multisite cohort study
Connolly KR, Helmer A, Cristancho MA, Cristancho P, O’Reardon JP. Effectiveness of transcranial magnetic stimulation in clinical practice…