The latest figures for Oxfordshire, show that about 14% of those aged between 16 and 64, or about 64,000 people, are economically inactive.
Starting with eight people in its first month, the programme in Oxfordshire will spend more than £4,000 on each job seeker, helping them to find and stay in work.
There are already 40 people on the waiting list for the scheme, which will be delivered by Oxfordshire County Council.
Through a similar inclusive programme, Jenny Taylor found a job at council’s in-house print company.
She said: “It’s trying to find employment that’s flexible and understanding and willing to help you when you’re down on your luck.
“I’ve just moved into my first home after living with my parents for 36 years. Gaining that independence was extremely important.”
The programme is free to take part and non-compulsory.
Will Gardener, lead officer for Connect to Work for the county council, said: “It’s the biggest programme of its type that we’ve seen in Oxfordshire for some time.
“For it to work, people need to want to take part. That is fundamental.”