Statins are a widely prescribed group of medicines used to lower the level of LDL cholesterol, often called “bad cholesterol,” in the blood

08:02, 11 Dec 2025Updated 11:11, 12 Dec 2025

pack of statinsStatins are a widely prescribed group of medicines used to lower the level of LDL cholesterol, often called “bad cholesterol,” in the blood(Image: PA)

The NHS warns people taking statins (to lower “bad cholesterol”) to call 999 immediately if they experience specific severe symptoms. These include sudden swelling or difficulty breathing, which signal a severe allergic reaction. Less critical but still serious symptoms, like unexplained muscle pain or yellowing skin, require calling 111.

Purpose of Statins: Statins are a widely prescribed group of medicines used to lower the level of LDL cholesterol, often called “bad cholesterol,” in the blood. By reducing cholesterol production in the liver, statins significantly reduce a person’s risk of severe events like strokes and heart attacks.Call 999 for Allergic Reactions: The NHS guidance stresses that patients should call 999 or go straight to A&E if they develop a severe allergic reaction. Key signs include the sudden swelling of lips, mouth, throat, or tongue, or if they are breathing very fast and struggling to breathe.Call 111 for Organ Damage Signs: For other serious, but not immediately life-threatening, side effects, patients should stop taking the medication and call 111 or a doctor immediately. This advice applies if they notice unexplained muscle pain (a sign of muscle breakdown) or if the whites of their eyes turn yellow (a sign of liver problems).Common, Mild Side Effects: Most people who take statins do not experience any side effects, but some mild symptoms are common and may include headaches, nausea, or cold-like symptoms. Patients should talk to their doctor or pharmacist if they get any side effects that bother them or do not quickly disappear.Liver and Stomach Warnings: The guidance specifically highlights symptoms that suggest damage to vital organs and require urgent attention. These include severe stomach pain, which can be a sign of acute pancreatitis, or a cough and shortness of breath, which can indicate lung disease.Different Statin Brands: The warning covers popular statin brands, including atorvastatin (Lipitor), simvastatin (Zocor), pravastatin (Lipostat), and rosuvastatin (Crestor). Doctors may recommend trying a lower dose or switching to a different statin type if a patient experiences bothersome side effects.