The £453,000 included a contribution from her late husband Robert Hess, whose passion for philanthropy, RPHC said, began after the premature death of his son in 1973.
Tomlin-Hess said: “Robert cared very much for my brother Terry and promised him that, after his surgery, when he was well enough to travel, Robert would treat him to a fishing trip in Alaska.”
Krystyna Grant, RPHC managing director, said: “We are overwhelmed by Wendy’s generosity and the potential of this gift to transform lives across the globe.
“Through Wendy’s support, Royal Papworth will continue to lead innovation in heart care and support, ensuring more patients receive the gift of life.”