Drivers experienced disruption and delay on Tuesday, January 20 as a result of planned works on the main road outside the hospital.
This was caused by a temporary failure of one of the traffic lights on the Kilmarnock side.
Contractors and Ayrshire Roads Alliance have now put additional measures in place to help improve traffic flow for the duration of the works.
Traffic lights will be staffed from 7am to 8.15pm, supported by a dedicated spotter on the A71 to adjust signal timings when traffic begins to build.
During the morning peak, priority will be given to traffic travelling from the Kilmarnock direction.
In the evening peak, priority will be given to vehicles exiting University Hospital Crosshouse via both the main exit and the East Car Park traffic lights.
The roadworks are expected to continue for approximately eight weeks.
Jacqueline Nicol, site director for University Hospital Crosshouse, added: “We ask staff and patients to allow extra time for the journey and, where possible, consider car sharing or alternative modes of transport for the duration of the works.”