Elliott said he wanted to do something “big” and “fun” to commemorate the 40th anniversary of the fundraiser.
The entertainer is best known for starring in The Chuckle Brothers, which was known for spawning catchphrases including “To me, to you” and “Oh dear, oh dear”.
He added: “Whilst I’d love to be able to cycle the iconic John O’Groats to Land’s End route like so many incredible fundraisers do, I’m really excited to get to travel the route with the Daff Bike, raise lots of money for the charity and meet as many Marie Curie supporters, volunteers and staff as possible to say a huge thank you – from me to you.”
Elliott’s tour of the UK will kick off on 3 March, with stops in Glasgow, Bradford, Birmingham, Penarth, Exeter and Plymouth, before his final stop in Land’s End on 11 March.
Marie Curie chief executive Matthew Reed said: “Every three minutes someone dies without the end-of-life care they need.
“The Great Daffodil Appeal gives Marie Curie the chance to provide expert end of life care and support to more people, whatever their illness. Care that protects someone’s dignity, instead of leaving them alone or in avoidable pain.
“A huge thank you to Paul for taking on this mammoth tour of the UK and thank you to our loyal supporters and volunteers for the last 40 years of support for the Great Daffodil Appeal.”