Lacie was four when she was diagnosed with acute lymphoblastic leukaemia, an aggressive form of blood cancer.

Her mum Jess, 37, noticed a lump on her daughter’s neck and how she was not being herself.

Over seven months, the family were told by doctors it was viral, or she had a cold.

Jess said: “It was horrible because Lacie was presenting so many signs before of just being ill.

“I never, ever thought of cancer, that never even entered my mind.”

It was not until Lacie had a high temperature that she was taken to Noah’s Ark Children’s Hospital in Cardiff and had a blood test.

“Being told Lacie had cancer just shattered our world and it was just, it was heart-breaking,” said Jess.

Three days after diagnosis, Lacie had surgery and started chemotherapy two hours later.

At that time another child who lives near to Jess and Lacie was also diagnosed with cancer.

“We’ve become inseparable. When the girls weren’t allowed to socialise we made the decision we would isolate them together. We made a bubble,” added Jess.

“The other families have been an amazing support. I can’t do life without them basically, and the children get on so well.”

The mothers set up a WhatsApp group which they use every day to chat.

Not just about their children but all aspects of life.

“I’ve got friends who are not in a part of this world, but they don’t understand on the level that the families do that I’m friendly with,” said Jess.

Over the last couple of years the mothers have participated in charity runs and the dads have taken on a skydive together.

The families now go on nights out, organise safe play dates for their children and go on holidays together.

Jess said: “We are planning a big group holiday abroad when all the children have finished their treatments.

“It’ll just continue and I can just see us doing more and more things together.”

Dr Simon Ridley, director of research and advocacy at Leukaemia UK, said: “It’s heart-warming to see that Lacie, Vinnie and their families have found support in this special group of friends.

“But their stories are a powerful reminder of the huge impact leukaemia can have on children and their families.”