Since being diagnosed, Issac, who is blood group O, has endured countless operations and emergency, close-call trips to hospital.
In October and November, he was admitted to Ipswich Hospital for enhanced dialysis and further treatments, spending about four weeks on a ward.
In December, having had little luck finding a suitable deceased kidney donor, Issac’s family was told it might be time to start looking for a living one.
His grandad said he had since been identified as the child most in need of a campaign for donorship by Gosh and Guy’s & St Thomas’ Hospital NHS Foundation Trust, in London.
Anita Copley, clinical nurse specialist in living kidney donations at Guy’s Hospital, helped them curate the appeal.
“It’s incredibly tough for these families, but the rewards are there when we do find a kidney donor for children,” she said.
“These lovely grandparents have learned how to perform dialysis, and they’re doing their very best, but it certainly is burdensome and taxing.”