Shackleton, S. et al. Miocene and Pliocene ice and air from the Allan Hills blue ice area, East Antarctica. Proc. Natl Acad. Sci. USA 122, e2502681122 (2025).
Marks Peterson, J. et al. Broadly stable atmospheric CO2 and CH4 levels over the past 3 million years. Nature https://doi.org/10.1038/s41586-025-10032-y (2026).
Clark, P. U., Shakun, J. D., Rosenthal, Y., Köhler, P. & Bartlein, P. J. Global and regional temperature change over the past 4.5 million years. Science 383, 884–890 (2024).
Shackleton, N. Oxygen isotope analyses and pleistocene temperatures re-assessed. Nature 215, 15–17 (1967).
Emiliani, C. Pleistocene temperatures. J. Geol. 63, 538–578 (1955).
Headly, M. A. & Severinghaus, J. P. A method to measure Kr/N2 ratios in air bubbles trapped in ice cores and its application in reconstructing past mean ocean temperature. J. Geophys. Res. 112, D19105 (2007).
Spaulding, N. E. et al. Ice motion and mass balance at the Allan Hills blue-ice area, Antarctica, with implications for paleoclimate reconstructions. J. Glaciol. 58, 399–406 (2012).
Yan, Y. et al. Two-million-year-old snapshots of atmospheric gases from Antarctic ice. Nature 574, 663–666 (2019).
Spaulding, N. E. et al. Climate archives from 90 to 250 ka in horizontal and vertical ice cores from the Allan Hills Blue Ice Area, Antarctica. Quat. Res. 80, 562–574 (2013).
Yan, Y. et al. Enhanced moisture delivery into Victoria Land, East Antarctica, during the early Last Interglacial: implications for West Antarctic Ice Sheet stability. Clim. Past 17, 1841–1855 (2021).
Shackleton, S. et al. Global ocean heat content in the Last Interglacial. Nat. Geosci. 13, 77–81 (2020).
Baggenstos, D. et al. Earth’s radiative imbalance from the Last Glacial Maximum to the present. Proc. Natl Acad. Sci. USA 116, 14881–14886 (2019).
Haeberli, M. et al. Snapshots of mean ocean temperature over the last 700 000 years using noble gases in the EPICA Dome C ice core. Clim. Past 17, 843–867 (2021).
Seltzer, A. M. et al. Dissolved gases in the deep North Atlantic track ocean ventilation processes. Proc. Natl Acad. Sci. USA 120, e2217946120 (2023).
Hamme, R. C., Emerson, S. R., Severinghaus, J. P., Long, M. C. & Yashayaev, I. Using noble gas measurements to derive air–sea process information and predict physical gas saturations. Geophys. Res. Lett. 44, 9901–9909 (2017).
Hamme, R. C. & Severinghaus, J. P. Trace gas disequilibria during deep-water formation. Deep Sea Res. I 54, 939–950 (2007).
Seltzer, A. M., Davidson, P. W., Shackleton, S. A., Nicholson, D. P. & Khatiwala, S. Global ocean cooling of 2.3 °C during the Last Glacial Maximum. Geophys. Res. Lett. 51, e2024GL108866 (2024).
Yun, K.-S. et al. A transient coupled general circulation model (CGCM) simulation of the past 3 million years. Clim. Past 19, 1951–1974 (2023).
Bender, M. L., Barnett, B., Dreyfus, G., Jouzel, J. & Porcelli, D. The contemporary degassing rate of 40Ar from the solid Earth. Proc. Natl Acad. Sci. USA 105, 8232–8237 (2008).
Higgins, J. A. et al. Atmospheric composition 1 million years ago from blue ice in the Allan Hills, Antarctica. Proc. Natl Acad. Sci. USA 112, 6887–6891 (2015).
Ford, H. L. & Raymo, M. E. Regional and global signals in seawater δ18O records across the mid-Pleistocene transition. Geology 48, 113–117 (2020).
Thomas, N. C., Ford, H. L., Greaves, M. & Hodell, D. A. Increased abyssal ocean density stratification across the Middle Pleistocene Transition. Preprint at https://doi.org/10.5194/egusphere-2025-4566 (2025).
Sosdian, S. & Rosenthal, Y. Deep-sea temperature and ice volume changes across the Pliocene-Pleistocene climate transitions. Science 325, 306–310 (2009).
Lear, C. H., Rosenthal, Y. & Wright, J. D. The closing of a seaway: ocean water masses and global climate change. Earth Planet. Sci. Lett. 210, 425–436 (2003).
Elderfield, H. et al. Evolution of ocean temperature and ice volume through the mid-Pleistocene climate transition. Science 337, 704–709 (2012).
Raymo, M. E. The initiation of Northern Hemisphere glaciation. Annu. Rev. Earth Planet. Sci. 22, 353–383 (1994).
Broccoli, A. J. & Manabe, S. The influence of continental ice, atmospheric CO2, and land albedo on the climate of the last glacial maximum. Clim. Dyn. 1, 87–99 (1987).
Liu, Z. et al. Transient simulation of last deglaciation with a new mechanism for Bølling-Allerød warming. Science 325, 310–314 (2009).
MartÃnez-Garcia, A., Rosell-Melé, A., McClymont, E. L., Gersonde, R. & Haug, G. H. Subpolar link to the emergence of the modern equatorial Pacific cold tongue. Science 328, 1550–1553 (2010).
Philander, S. G. & Fedorov, A. V. Role of tropics in changing the response to Milankovich forcing some three million years ago. Paleoceanography https://doi.org/10.1029/2002PA000837 (2003).
Shackleton, S., Seltzer, A., Baggenstos, D. & Lisiecki, L. E. Benthic δ18O records Earth’s energy imbalance. Nat. Geosci. 16, 797–802 (2023).
Westerhold, T. et al. An astronomically dated record of Earth’s climate and its predictability over the last 66 million years. Science 369, 1383–1387 (2020).
Shackleton, N. J. Attainment of isotopic equilibrium between ocean water and the benthonic foraminifera genus Uvigerina: isotopic changes in the ocean during the last glacial. Colloq. Int. CNRS 219, 203–210 (1974).
Winnick, M. J. & Caves, J. K. Oxygen isotope mass-balance constraints on Pliocene sea level and East Antarctic Ice Sheet stability. Geology 43, 879–882 (2015).
Clark, P. U. et al. Global mean sea level over the past 4.5 million years. Science 390, eadv8389 (2025).
Clark, P. U. et al. Mean ocean temperature change and decomposition of the benthic δ18O record over the past 4.5 million years. Clim. Past 21, 973–1000 (2025).
Dole, M. The relative atomic weight of oxygen in water and in air. J. Am. Chem. Soc. 57, 2731–2731 (1935).
Landais, A. et al. What drives the millennial and orbital variations of δ18Oatm?. Quat. Sci. Rev. 29, 235–246 (2010).
Severinghaus, J. P., Beaudette, R., Headly, M. A., Taylor, K. & Brook, E. J. Oxygen-18 of O2 records the impact of abrupt climate change on the terrestrial biosphere. Science 324, 1431–1434 (2009).
Bender, M., Sowers, T. & Labeyrie, L. The Dole effect and its variations during the last 130,000 years as measured in the Vostok Ice Core. Global Biogeochem. Cycles 8, 363–376 (1994).
Raymo, M. E., Kozdon, R., Evans, D., Lisiecki, L. & Ford, H. L. The accuracy of mid-Pliocene δ18O-based ice volume and sea level reconstructions. Earth Sci. Rev. 177, 291–302 (2018).
Kuhl, T. W. et al. A new large-diameter ice-core drill: the Blue Ice Drill. Ann. Glaciol. 55, 1–6 (2014).
Seltzer, A. M. & Bekaert, D. V. A unified method for measuring noble gas isotope ratios in air, water, and volcanic gases via dynamic mass spectrometry. Int. J. Mass Spectrom. 478, 116873 (2022).
Schwander, J. in The Environmental Record in Glaciers and Ice Sheets (eds Oeschger, H. & Langway, C. C.) 53–67 (Wiley, 1989).
Craig, H., Horibe, Y. & Sowers, T. Gravitational separation of gases and isotopes in polar ice caps. Science 242, 1675–1678 (1988).
Sowers, T., Bender, M. & Raynaud, D. Elemental and isotopic composition of occluded O2 and N2 in polar ice. J. Geophys. Res. 94, 5137–5150 (1989).
Bereiter, B., Shackleton, S., Baggenstos, D., Kawamura, K. & Severinghaus, J. Mean global ocean temperatures during the last glacial transition. Nature 553, 39–44 (2018).
Jenkins, W. J., Lott, D. E. & Cahill, K. L. A determination of atmospheric helium, neon, argon, krypton, and xenon solubility concentrations in water and seawater. Mar. Chem. 211, 94–107 (2019).
Lambeck, K., Rouby, H., Purcell, A., Sun, Y. & Sambridge, M. Sea level and global ice volumes from the Last Glacial Maximum to the Holocene. Proc. Natl Acad. Sci. USA 111, 15296–15303 (2014).
Pöppelmeier, F. et al. The effect of past saturation changes on noble gas reconstructions of mean ocean temperature. Geophys. Res. Lett. 50, e2022GL102055 (2023).
Cutler, K. B. et al. Rapid sea-level fall and deep-ocean temperature change since the last interglacial period. Earth Planet. Sci. Lett. 206, 253–271 (2003).
Charette, M. & Smith, W. The volume of Earth’s ocean. Oceanography 23, 112–114 (2010).
Willeit, M. et al. Mid-Pleistocene transition in glacial cycles explained by declining CO2 and regolith removal. Sci. Adv. 5, eaav7337 (2019).
Dumitru, O. A. et al. Sea-level stands from the Western Mediterranean over the past 6.5 million years. Sci. Rep. 11, 261 (2021).