Passengers are being warned that the Tyne and Wear Metro will be “shut down” to allow the replacement of old equipment.
Systems controlling critical safety functions, including overhead power lines, lighting and fire alarms, are being upgraded at its base in South Gosforth.
Trains will not run across the entire network on Easter Monday between 05:00 and 10:00 BST and there will be no trains between Pelaw and South Hylton from 23:30 on Sunday 3 May until 10:30 the following morning.
Metro operator Nexus has warned passengers to allow extra time for journeys, which will be served by replacement buses.