Aleks will be driven from Ukraine through Poland and northern Europe and then from Dover to his new home at the wildlife park at Friskney in Lincolnshire.
Before his rescue and treatment, the tiger was dehydrated, infested with parasites and exhausted, as well as having gastrointestinal issues, and liver and kidney issues, the park said.
Mr Nichols said the park had got almost everything ready for Aleks following a fundraising campaign set up to help cover the £100,000 cost of his new enclosure.
A gate was installed at his enclosure on Monday, leaving a swimming pool and play frame as the final items to be added.