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We examine the rise and risks of blockbuster drugs like Ozempic, after the WHO conditionally recommended GLP-1s for the long-term treatment of obesity.

CBC News · Posted: Dec 11, 2025 4:00 AM EST | Last Updated: December 11

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Two boxes and a blue injector pen.Ozempic boxes and injector. (Turgut Yeter/CBC)LISTEN | FRONT BURNER:

Front Burner25:34Should everybody be taking Ozempic?

It’s estimated that as many as 10 per cent of adults in Canada use a GLP-1 type drug like Ozempic. The prescription medicine is used for type 2 diabetes management and increasingly prescribed off-label for weight loss. And this month, for the first time, the World Health Organization has conditionally recommended GLP-1 drugs for the long-term treatment of obesity.

But while these drugs have been called a game-changing tool to manage a complex and stigmatized health condition, there’s also a lot of questions about the potential negative impact.

With Ozempic’s patent set to expire soon in Canada, and more affordable generic options about to hit the market, a lot more people you know could end up on a weight-loss drug.

Today we bring you the rise and risks of GLP-1s with help from Dylan Scott. He is a Senior Correspondent at Vox who covers health.

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