The trail begins in, external Paulsgrove and finishes in Southsea, with 45 lions and one unicorn statue to find.
Artists, included well-known local names and new talent, were asked to design a lion inspired by the people, coastline and heritage of Portsmouth.
One of the artists involved includes Or Misgav, who recently moved to Portsmouth.
Or said painting a lion for the trail was a good way to give back to the city.
She said: “The city was so welcoming and it just invited me in, and I wanted to create something and give back to the community.
“So my lion is kind of a love letter for Portsmouth.”
The lion she’s decorated represents data from the people of Portsmouth.
She added: “I really hope people will come and engage with it because my piece is not just about just seeing it.
“It’s about coming closer, looking at the data, and looking at it from different perspective.”