Chromatix: a differentiable, GPU-accelerated wave-optics library
Design and implementation The design of Chromatix is strongly inspired by current deep learning frameworks. Here we detail…
Why a synthetic human genome is still worth building
Ten years ago, when I was a first-year graduate student, my PhD adviser smuggled me into a private…
Fetal monitoring for high-risk pregnancies using a wearable ultrasound patch
Woodward, P. J., Kennedy, A. & Sohaey, R. Diagnostic Imaging: Obstetrics 4th edn (Elsevier, 2021). Hutter, D., Kingdom,…
Researchers Finally Solve 50-Year-Old Blood Group Mystery
Researchers have identified a previously overlooked mechanism that alters how strongly certain blood group genes are expressed, revealing…
Multimodal learning enables chat-based exploration of single-cell data
Multimodal training data of paired transcriptomes and text To establish a large training dataset of transcriptomes and their…
World Record Set For Fastest Genome Sequencing | Health
Key Takeaways Researchers have set a new world record for fastest whole human genome sequencing The team completed…
World Record Set For Fastest Genome Sequencing | Health
Key Takeaways Researchers have set a new world record for fastest whole human genome sequencing The team completed…
SPAmix: a scalable, accurate, and universal analysis framework for large-scale genetic association studies in admixed populations | Genome Biology
Model residuals of linear regression and logistic regression Linear regression and logistic regression are regular models to fit…
SAGPEK: fast and flexible approach to identify genotypes of Sanger sequencing data | BMC Bioinformatics
Software architecture SAGPEK mainly processes Sanger sequencing results of two kinds of samples: diploids such as humans and…
A novel gene expression stability metric to unveil homeostasis and regulation | Genome Biology
K-proportion and gene homeostasis Z-Index identify regulatory genes As cells of the same type and in the same…
Incorporating additive genetic effects and linkage disequilibrium information to discover gene-environment interactions using BV-LDER-GE | Genome Biology
Model overview We consider the following model to incorporate both additive and interaction effects: $${Y}_{i}={\sum }_{j=1}^{M}{G}_{ji}{\beta }_{j}+{\sum }_{j=1}^{M}{S}_{ji}{\gamma…
Advances in haplotype phasing and genotype imputation
Voight, B. F., Kudaravalli, S., Wen, X. & Pritchard, J. K. A map of recent positive selection in…