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Browsing Tag

Biomedicine

42 posts
GGenetics
Single-nucleus chromatin accessibility profiling identifies cell types and functional variants contributing to major depression
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Single-nucleus chromatin accessibility profiling identifies cell types and functional variants contributing to major depression

  • August 6, 2025
James, S. L. et al. Global, regional, and national incidence, prevalence, and years lived with disability for 354…
GGenetics
Uncovering the multivariate genetic architecture of frailty with genomic structural equation modeling
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Uncovering the multivariate genetic architecture of frailty with genomic structural equation modeling

  • August 5, 2025
Fogg, C. et al. The dynamics of frailty development and progression in older adults in primary care in…
GGenetics
Predicting resistance to chemotherapy using chromosomal instability signatures
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Predicting resistance to chemotherapy using chromosomal instability signatures

  • August 2, 2025
CIN signatures as biomarkers of chemotherapy resistance The presence of CIN in a tumor has long been recognized…
GGenetics
Detecting and quantifying clonal selection in somatic stem cells
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Detecting and quantifying clonal selection in somatic stem cells

  • August 2, 2025
Ethical approval Patient samples were collected with informed consent under the Mechanisms of Age-Related Clonal Haematopoiesis (MARCH) Study.…
GGenetics
Pangenome analysis provides insights into legume evolution and breeding
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Pangenome analysis provides insights into legume evolution and breeding

  • July 31, 2025
Foyer, C. H. et al. Neglecting legumes has compromised human health and sustainable food production. Nat. Plants 2,…
GGenetics
Methods and applications of in vivo CRISPR screening
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Methods and applications of in vivo CRISPR screening

  • July 29, 2025
Auton, A. et al. A global reference for human genetic variation. Nature 526, 68–74 (2015). Google Scholar  García-García,…
GGenetics
Towards improved fine-mapping of candidate causal variants
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Towards improved fine-mapping of candidate causal variants

  • July 29, 2025
Visscher, P. M. et al. 10 years of GWAS discovery: biology, function, and translation. Am. J. Hum. Genet.…
HHealthcare
A consensus statement on the use of digital twins in medicine
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A consensus statement on the use of digital twins in medicine

  • July 29, 2025
The DT is a generic instrument able to integrate different technologies applicable across the disease (and indeed health)…
GGenetics
Integrated in vivo combinatorial functional genomics and spatial transcriptomics of tumours to decode genotype-to-phenotype relationships
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Integrated in vivo combinatorial functional genomics and spatial transcriptomics of tumours to decode genotype-to-phenotype relationships

  • July 29, 2025
Animal experiments Group size was determined on the basis of our experience in previous experiments68,69. For HDTV injections,…
GGenetics
Large-scale genome-wide analyses of stuttering
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Large-scale genome-wide analyses of stuttering

  • July 28, 2025
Yairi, E. & Ambrose, N. Epidemiology of stuttering: 21st century advances. J. Fluen. Disord. 38, 66–87 (2013). Google…
GGenetics
Genetic variation in the activity of a TREM2–p53 signaling axis determines oxygen-induced lung injury
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Genetic variation in the activity of a TREM2–p53 signaling axis determines oxygen-induced lung injury

  • July 26, 2025
Pryhuber, G. S. et al. Prematurity and respiratory outcomes program (PROP): study protocol of a prospective multicenter study…
UUnited Kingdom
Sociodemographic factors associated with health-related quality of life in UK healthcare workers: a cross-sectional study | BMC Medicine
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Sociodemographic factors associated with health-related quality of life in UK healthcare workers: a cross-sectional study | BMC Medicine

  • July 22, 2025
ONS: International migration and the healthcare workforce Office for National Statistics. Office for National Statistics. 2019. Available from:…
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