Biomedicine - United Kingdom News Beep

Systematic review of cost effectiveness and budget impact of artificial intelligence in healthcare

August 27, 2025

This systematic review synthesized economic evidence from 19 diverse clinical AI interventions across multiple specialties, demonstrating consistent clinical…

FFitness

New perspectives on molecular mechanisms underlying exercise-induced benefits in Parkinson’s disease

August 25, 2025

Poewe, W. et al. Parkinson disease. Nat. Rev. Dis. Prim. 3, 17013 (2017). PubMed Google Scholar Stocchi, F.…

GGenetics

Systema: a framework for evaluating genetic perturbation response prediction beyond systematic variation

August 25, 2025

Nonparametric baselines We design two nonparametric baselines that we refer to as perturbed mean and matching mean. Perturbed…

GGenetics

Precise modulation of BRG1 levels reveals features of mSWI/SNF dosage sensitivity

August 25, 2025

BRG1 binding exhibits a linear response to its dosage In mES cells, Brg1 encodes the major catalytic subunit…

GGenetics

Genetic susceptibility to caffeine intake and metabolism: a systematic review | Journal of Translational Medicine

August 25, 2025

Coffee and Caffeine Genetics Consortium, Cornelis MC, Byrne EM, et al. Genome-wide meta-analysis identifies six novel loci associated…

GGenetics

Temporal genomic dynamics shape clinical trajectory in multiple myeloma

August 23, 2025

Maura, F. et al. Moving from cancer burden to cancer genomics for smoldering myeloma: a review. JAMA Oncol.…

GGenetics

Imaging-based multimodal profiling of single cells with STAMP

August 22, 2025

Single-cell RNA sequencing (scRNA-seq) has dramatically advanced our ability to dissect complex biological systems at cellular resolution. However,…

GGenetics

KidneyGenAfrica, a pan-African partnership to deliver research and training excellence in genomics of kidney disease

August 22, 2025

Precision Healthcare University Research Institute, Queen Mary University of London, London, UK Segun Fatumo, Oyesola Ojewunmi, Rebecca Camenzuli, Christopher Kintu & Claudia Langenberg…

GGenetics

Genetic and molecular landscape of comorbidities in people living with HIV

August 22, 2025

Participants from the 2000HIV study The 2000HIV study is a prospective multicentric observational longitudinal cohort of virally suppressed…

GGenetics

A comparison of 27 Arabidopsis thaliana genomes and the path toward an unbiased characterization of genetic polymorphism

August 20, 2025

DNA extraction and sequencing For long-read sequencing, we began with 3-week-old plants grown in soil that had been…

AArtificial intelligence

AI-driven reclassification of multiple sclerosis progression

August 20, 2025

Analysis set from the NO.MS database The NO.MS database was previously described20. In brief, it comprises 39 clinical…

GGenetics

Tracing the evolution of sequencing into the era of genomic medicine

August 16, 2025

Sanger, F., Nicklen, S. & Coulson, A. R. DNA sequencing with chain-terminating inhibitors. Proc. Natl Acad. Sci. USA…