Health system learning enables generalist neuroimaging models
Health system learning We define ‘health system learning’ as learning directly from uncurated data generated during routine clinical…
A blended genome and exome sequencing method captures genetic variation in an unbiased and cost-effective manner
Ethics approval and consent to participate All cohorts involving human participants that were included in this research have…
Identifying critical lysines in mammalian histone H3 with high-throughput CRISPR prime editing
Adapting prime editing for mammalian histone mutagenesis Mouse canonical histone H3 is encoded by nine H3.1 and three…
Generative AI-enabled clinical decision support system in primary care: a pragmatic, cluster-randomized trial
Design We conducted a pragmatic, multicenter, parallel-group cluster-randomized controlled trial across a network of 16 primary care facilities…
Evaluating the robustness and readiness of large frontier models in health AI applications
Singhal, K. et al. Large language models encode clinical knowledge. Nature 620, 172–180 (2023). Article CAS PubMed PubMed…
Johnson & Johnson CEO says cancer cure could come within a decade
NEWYou can now listen to Fox News articles! A cure for cancer could be on the horizon in…
The promise of adaptive health in the United Arab Emirates and beyond
Department of Medicine, Johns Hopkins University, Baltimore, MD, USA Andrew P. Feinberg Department of Biomedical Engineering, Johns Hopkins…
Towards mRNA therapeutics 2.0 | Nature Reviews Drug Discovery
Kallen, K.-J. et al. A novel, disruptive vaccination technology: self-adjuvanted RNActive® vaccines. Hum. Vaccin. Immunother. 9, 2263–2276 (2013). Article …
MAGE-A4/MAGE-A8-targeted TCR-based bispecific T cell engager in recurrent and/or refractory solid tumors: a phase 1 trial
Study conduct The trial was conducted from 19 May 2022 to 2 March 2026 (data cutoff date) in…
AI-induced never-skilling in medical education
Bajwa, J., Munir, U., Nori, A. & Williams, B. Artificial intelligence in healthcare: transforming the practice of medicine.…
Mum loses ‘perfect child’ just 15 days after first symptom and issues plea
Mum Amanda Axiak lost her 11-year-old daughter last year “In her short final days, Alicia remained her selfless,…
Advancing conversational diagnostic AI with multimodal reasoning
This work advances the diagnostic capabilities of the multimodal AMIE system4,5 by integrating multimodal perception, enabling it to…