All the ways a cell can die — and why the variety matters
The cells in Daolin Tang’s Petri dishes were dead. Signs of life had dropped off a cliff; they…
RamanOmics decodes the spatial vibrational–molecular architecture of senescence in aging and repair
Multimodal characterization and identification of aging and senescence through RamanOmics To investigate the cellular and molecular characteristics of…
Reconciling the neurogenic hypothesis of depression with recent advances in adult hippocampal neurogenesis research in humans
World Health Organization. Depressive disorder (depression) 2025 [Available from: https://www.who.int/news-room/fact-sheets/detail/depression. Lucassen PJ, Fitzsimons CP, Korosi A, Joels M,…
These bizarre, much-coveted microbes are revealing the origins of complex life
Over two days in June, Emily Aguilar-Pine drove 2,500 kilometres from Bozeman, Montana, to Austin, Texas, with one…
Probing the proteome at cellular scale
When a fertilized mammalian egg divides, it yields two seemingly identical daughter cells. Some of their descendants generate…
Probiotics may help protect against sarcopenia in older adults
Researchers used three approaches to study whether probiotics could help prevent sarcopenia (age-related loss of muscle mass, strength…
SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry
Bostick, M. et al. UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science 317, 1760–1764…
Why do astronauts’ bodies waste away? Space-station study points to mitochondria
The mitochondrion (green in this false-colour transmission electron micrograph) could have a role in the physiological effects of…
World-first: therapy to make cells young again given to a person
Scientists are attempting to rejuvenate cells in the optic nerve (nerve fibres in red), which channels information from…
Bang! Exploding immune cells splatter potent toxins everywhere
Intact immune cells (left column) had disintegrated (right column) only 100 seconds after their explosion was triggered by…
Scientists Discover a Hidden Cause of Cellular Aging That Can Be Reversed
Scientists have uncovered a surprising link between aging cells and a membrane lipid that helps mitochondria stay flexible…
Stanford’s Revolutionary New Microscope Reveals Living Cells in Stunning Detail
Detail of the laser array that is part of the Interferometric Image Scanning Microscopy technology. Credit: Jim Gensheimer…