How to build a mouse: embryo development captured in stunning detail
By introducing and tracking mutations as the cells of a mouse embryo divide, researchers have mapped relationship between…
Bizarre CRISPR enzyme kills cancer cells by shredding their DNA
A bacterial enzyme that indiscriminately slashes DNA (artist’s illustration) has been harnessed to kill cancer cells. Credit: KTSDesign/Science…
CRISPR gets a power boost from AI-designed ‘molecular scissors’
An enzyme cuts DNA (artist’s impression). Synthetic protein-cleaving enzymes were designed quickly with the help of artificial intelligence.Credit:…
Epigenetic editing makes its mark
Epigenetic modifications to DNA (yellow), such as those catalysed by DNA methyltransferase enzymes (blue, centre) control gene expression.Credit:…
versatile gene-editing tool could tackle a host of diseases
A cell’s protein-making machinery (artist’s illustration) can be instructed to ignore mutations that would otherwise result in shortened…
can gene editing prevent heart disease?
Crystalline forms of cholesterol (blue) in a liver cell (purple), imaged using a scanning electron microscope.Credit: Steve Gschmeissner/Science…
Real-time molecular recorders expose the inner lives of cells
Illustration: The Project Twins Cells are poor storytellers. They live complex, eventful lives — dividing, migrating, responding to…
the gene-altering tools tackling deadly disorders
Brain cells (artificially coloured) can be infected by a virus carrying the apperatus to correct disease-causing mutations. Credit:…