Electric dipole moment drives the dynamics of the TNFR1 complex I signalosome
Micheau, O. & Tschopp, J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114,…
Convergent MurJ flippase inhibition by phage lysis proteins
Murray, C. J. L. et al. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet…
Targeting mGlyR with nanobodies for depression
Animals All animal experiments were approved by the Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology…
Molecular mechanism of ultrafast transport by plasma membrane Ca2+-ATPases
Luan, S. & Wang, C. Calcium signaling mechanisms across kingdoms. Annu. Rev. Cell Dev. Biol. 37, 311–340 (2021).…
SLC45A4 is a pain gene encoding a neuronal polyamine transporter
Study Population The UKB is a prospective cohort study that has collected extensive phenotypic and genetic data from…