New lab-grown human embryo model produces blood cells
University of Cambridge scientists have used human stem cells to create three-dimensional embryo-like structures that replicate certain aspects…
CellNavi predicts genes directing cellular transitions by learning a gene graph-enhanced cell state manifold
Input embeddings In CellNavi, we use single-cell raw count matrices as the only input. Specifically, the single-cell sequencing…
Real-time molecular recorders expose the inner lives of cells
Illustration: The Project Twins Cells are poor storytellers. They live complex, eventful lives — dividing, migrating, responding to…
Spatial architecture of development and disease
Bressan, D., Battistoni, G. & Hannon, G. J. The dawn of spatial omics. Science 381, eabq4964 (2023). Article …
Systematic decoding of functional enhancer connectomes and risk variants in human glioma
The study was approved by the Ethics Institutional Review Boards of the First Affiliated Hospital of Sun Yat-sen…
Programmable Chromosome Engineering systems enable precise DNA manipulations
A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology…