Genetic trade-offs in fertility and longevity explain the maintenance of disease-associated alleles in humans
Welter, D. et al. The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic Acids Res. 42,…
Complex multicellularity is linked with expanded specialized metabolite production in microorganisms
Fischbach, M. A., Walsh, C. T. & Clardy, J. The evolution of gene collectives: how natural selection drives…
Gene ancestries reveal diverse microbial associations during eukaryogenesis
Data retrieval, curation and proteome database reconstructioneTOLDB construction To guide dataset selection and LECA reconstruction, we used the…
Distinct genetic architecture in the tails of complex traits
Data processingUKB genotype data The UKB is a prospective cohort study of approximately 500,000 participants recruited across the…
Adaptive cellular evolution in the intestine of hyperdiverse cichlid fishes
Darwin, C. On the Origin of Species (Cambridge Univ. Press, 1859). Simpson, G. G. The Major Features of…
Chromosomal fusions trigger rediploidization of autopolyploid genomes
Ohno, S. Evolution by Gene Duplication (Springer, 1970). Dehal, P. & Boore, J. L. Two rounds of whole…
Tumour promotion through the lens of evolution
Nowell, P. C. The clonal evolution of tumor cell populations. Science 194, 23–28 (1976). Article CAS PubMed ADS …
Ancient DNA reveals pervasive directional selection across West Eurasia
Liu, Y., Mao, X., Krause, J. & Fu, Q. Insights into human history from the first decade of…
The genomic history of Iberian horses since the last Ice Age
Genome data set A total of 87 horse archaeological remains, including petrosal bones, teeth and postcranial elements, were…
A male-essential miRNA is key for avian sex chromosome dosage compensation
Ethics information All animal procedures were conducted in compliance with national and international ethical guidelines and regulations. Mouse…