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Browsing Tag

general

356 posts
GGenetics
Targeted in vivo gene integration of a secretion-enabled GLP-1 receptor agonist reverses diet-induced non-genetic obesity and pre-diabetes
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Targeted in vivo gene integration of a secretion-enabled GLP-1 receptor agonist reverses diet-induced non-genetic obesity and pre-diabetes

  • July 19, 2025
Plasmid construction The Exe4 gene was codon-optimized using the GeneSmart codon optimization tool (https://www.genscript.com/gensmart-free-gene-codon-optimization.html) based on the amino…
GGenetics
Decomposition of phenotypic heterogeneity in autism reveals underlying genetic programs
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Decomposition of phenotypic heterogeneity in autism reveals underlying genetic programs

  • July 19, 2025
Identifying the structures of autism phenotypes To best reflect the complexity of presentations across autistic individuals, we identified…
GGenetics
Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy
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Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy

  • July 19, 2025
Cancer is a genetic disease stemming from a combination of inherited and acquired mutations. Much of our understanding…
PPhysics
Typical thermalization of low-entanglement states
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Typical thermalization of low-entanglement states

  • July 19, 2025
The micro-canonical ensemble is commonly defined as the maximally mixed state-supported in a narrow window around a fixed…
SSpace
NASA Tests Scalable Satellite Tech to Launch Sensors Quicker
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NASA Tests Scalable Satellite Tech to Launch Sensors Quicker

  • July 19, 2025
NASA’s Athena Economical Payload Integration Cost mission, or Athena EPIC, is a test launch for an innovative, scalable…
PPhysics
Elastic properties of force-transmitting linkages determine multistable mechanosensitive behaviour of cell adhesion
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Elastic properties of force-transmitting linkages determine multistable mechanosensitive behaviour of cell adhesion

  • July 19, 2025
Semi-analytical mechanical model of cell-adhesion complexes To study the potential effect of the elastic properties of molecular clutches…
EEnvironment
Thermal adaptation of respiration in terrestrial ecosystems alleviates carbon loss
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Thermal adaptation of respiration in terrestrial ecosystems alleviates carbon loss

  • July 19, 2025
Friedlingstein, P. et al. Global carbon budget 2022. Earth Syst. Sci. Data 14, 4811–4900 (2022). Google Scholar  Luo,…
UUnited Kingdom
A mixed methods formative evaluation of the United Kingdom National Health Service Artificial Intelligence Lab
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A mixed methods formative evaluation of the United Kingdom National Health Service Artificial Intelligence Lab

  • July 17, 2025
We interviewed 85 individuals, reviewed 1021 documents, and conducted 12 observations. A detailed description of the dataset is…
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