Efficient sequence alignment against millions of prokaryotic genomes with LexicMap
Probe generation Probes, also referred to as ‘masks’ in the LexicHash paper, consist of a fixed number (m = 20,000…
Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair
PacBio Revio HiFiPCR-free Revio HiFi Sequencing (Dataset ID: PB-HiFi-1) Library Preparation Library preparation was performed using previously isolated…
Genetic variation at transcription factor binding sites largely explains phenotypic heritability in maize
Quantification of functional cis-variation To focus on genetic differences affecting TF binding in cis, we quantified TF footprints…
Structural variation in 1,019 diverse humans based on long-read sequencing
Samples and DNA extraction We initially selected 1,064 samples from the 1kGP collection, sourcing genomic DNA from Coriell…
Complex genetic variation in nearly complete human genomes
Liao, W.-W. et al. A draft human pangenome reference. Nature 617, 312–324 (2023). ADS PubMed PubMed Central CAS …