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Browsing Tag

Genome-wide association studies

30 posts
GGenetics
Genome-wide analysis of brain age identifies 59 associated loci and unveils relationships with mental and physical health
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Genome-wide analysis of brain age identifies 59 associated loci and unveils relationships with mental and physical health

  • October 6, 2025
Ethical approval This study used individual-level data from the UKB (www.ukbiobank.ac.uk) and LIFE-Adult (www.uniklinikum-leipzig.de/einrichtungen/life)26,29,30. Both studies were conducted…
GGenetics
A genetic map of human metabolism across the allele frequency spectrum
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A genetic map of human metabolism across the allele frequency spectrum

  • October 4, 2025
Study design The UKB is a prospective cohort study from the UK that contains more than 500,000 volunteers…
HHealth
Polygenic and developmental profiles of autism differ by age at diagnosis
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Polygenic and developmental profiles of autism differ by age at diagnosis

  • October 2, 2025
Department of Psychiatry, University of Cambridge, Cambridge, UK Xinhe Zhang, Yuanjun Gu, Sharon A. S. Neufeld, Simon Baron-Cohen & Varun Warrier Autism Research…
GGenetics
Advances in haplotype phasing and genotype imputation
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Advances in haplotype phasing and genotype imputation

  • September 24, 2025
Voight, B. F., Kudaravalli, S., Wen, X. & Pritchard, J. K. A map of recent positive selection in…
GGenetics
Genetic architecture of plasma metabolome in 254,825 individuals
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Genetic architecture of plasma metabolome in 254,825 individuals

  • September 20, 2025
Population characteristics We included 254,825 UKB participants with both metabolomic and genomic data available after quality control. The…
GGenetics
Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects
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Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects

  • September 18, 2025
Abul-Husn, N. S. & Kenny, E. E. Personalized medicine and the power of electronic health records. Cell 177,…
GGenetics
Digital illustration of the human digestive system
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Human Genome and Gut Fungi Interact in Chronic Disease Risk

  • September 5, 2025
Credit: dimdimich / Getty Images A genome-wide association study has revealed how a person’s unique genetic makeup can…
GGenetics
Research uncovers gene variant role in disease biology
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Research uncovers gene variant role in disease biology

  • August 29, 2025
Immune New research has filled in missing links between gene variants that have been implicated in disease through…
GGenetics
Research uncovers gene variant role in disease biology
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Research uncovers gene variant role in disease biology

  • August 28, 2025
New research has filled in missing links between gene variants that have been implicated in disease through genome-wide…
GGenetics
African American ancestry study identifies new lung cancer risk factors
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African American ancestry study identifies new lung cancer risk factors

  • August 25, 2025
Cancer Despite having lower smoking habits than other groups in the U.S., Black Americans are more likely to…
GGenetics
Genome-wide association meta-analysis of human olfactory identification discovers sex-specific and sex-differential genetic variants
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Genome-wide association meta-analysis of human olfactory identification discovers sex-specific and sex-differential genetic variants

  • August 22, 2025
Kadohisa, M. Effects of odor on emotion, with implications. Front. Syst. Neurosci. 7, 57047 (2013). Zucco, G. M.,…
HHealth
SLC45A4 is a pain gene encoding a neuronal polyamine transporter
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SLC45A4 is a pain gene encoding a neuronal polyamine transporter

  • August 21, 2025
Study Population The UKB is a prospective cohort study that has collected extensive phenotypic and genetic data from…
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