How bacterial immune systems sense phage infection
Georjon, H. & Bernheim, A. The highly diverse antiphage defence systems of bacteria. Nat. Rev. Microbiol. 21, 686–700…
Ambient temperature is encoded in the metagenome of microbial communities
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This…
Phenomic profiles and disease patterns of 1.9 million participants from Our Future Health
Ethical approval This study involves data from human participants that have participated in the OFH program and the…
Histological aging signatures for monitoring tissue-specific aging and disease
Data reporting No statistical methods were used to predetermine sample size due to the predetermined sample availability of…
Psilocybin-assisted therapy for treatment-resistant major depressive disorder in a public healthcare setting: a randomized controlled trial
This study of psilocybin assisted-therapy for TRD—to our knowledge, the first RCT in this population to assess feasibility…
Divergent impacts of explainable AI for dermatological diagnosis on clinicians versus lay people
Study design We designed two complementary large-scale experiments to evaluate human−AI collaborative diagnostic performance across expertise levels (Fig.…
Impacts of pollution on the soil microbiome
Rodríguez-Eugenio, N., McLaughlin, M. & Pennock, D. Soil Pollution: A Hidden Reality (FAO, 2018). Montanerella, L. et al.…
Integrated care pathway in individuals with Long COVID: STIMULATE-ICP, a cluster-randomized, phase 3 trial
Trial design and oversight The STIMULATE-ICP trial aimed to investigate the efficacy of an enhanced ICP for LC,…
Within-patient gene transfer between transiently and chronically infecting bacteria causes extreme antibiotic resistance during lung infections
Murray, C. J. L. et al. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet…
Mapping in-cell protein contact sites reveals hijacking of paraspeckles during influenza A virus infection
Immortalized cell lines Human A549 (86012804; ECACC) and HEK293T (CRL-3216; ATCC) cells were cultured in DMEM (11960044; Gibco)…
Health system learning enables generalist neuroimaging models
Health system learning We define ‘health system learning’ as learning directly from uncurated data generated during routine clinical…
Marburg virus cases reported in Ugandan ebola outbreak area
Uganda formally reported to the World Health Organization on Tuesday that it had detected a Marburg disease outbreak…