Reassurance through normalization inadvertently suppresses treatment
Kessel, N. Reassurance. Lancet 313, 1128–1133 (1979). Article Google Scholar Giroldi, E. et al. ‘No need to worry’:…
Impacts of pollution on the soil microbiome
Rodríguez-Eugenio, N., McLaughlin, M. & Pennock, D. Soil Pollution: A Hidden Reality (FAO, 2018). Montanerella, L. et al.…
Short-chain fatty acids | Nature Metabolism
Ji, X. et al. Butyrate stimulates hepatic gluconeogenesis in mouse primary hepatocytes. Exp. Ther. Med. 17, 1677–1687 (2019).…
Low carbohydrate high fat diet curbs glioblastoma by shifting lipids and limiting cancer stem cell metabolic flexibility
Metabolic rewiring fuels tumorigenicity of cancer stem cells contributing to universal glioblastoma (GBM) recurrence. Invasive glioblastoma stem cells…
Within-patient gene transfer between transiently and chronically infecting bacteria causes extreme antibiotic resistance during lung infections
Murray, C. J. L. et al. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet…
Distinct brain regions mediate regulation of food intake in response to GIPR agonism or antagonism
Dual agonism of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors (GLP-1R and GIPR, respectively), in the…
Increased nutrient diversity can induce loss of microbial diversity through enhanced resource uptake
Media and bacterial culture Bacteria were precultured from frozen stocks in nutrient medium (NM) composed of 1% yeast…
Mapping in-cell protein contact sites reveals hijacking of paraspeckles during influenza A virus infection
Immortalized cell lines Human A549 (86012804; ECACC) and HEK293T (CRL-3216; ATCC) cells were cultured in DMEM (11960044; Gibco)…
Genetic trade-offs in fertility and longevity explain the maintenance of disease-associated alleles in humans
Welter, D. et al. The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic Acids Res. 42,…
Rates of passerine body plan evolution in time and space
Jablonski, D., Roy, K. & Valentine, J. W. Out of the tropics: evolutionary dynamics of the latitudinal diversity…
Spatial mapping and senolytic targeting of senescent and disease-associated microglia in aged mouse brain white matter
Expression of DAM and senescence genes, including p16 ink4a and Lgals3, increase in aged brain white matter We…
A data-driven framework reconstructs the molecular continuum of human MASLD progression
Transcriptomics-based disease trajectory analysis captures MASLD progression We first sought to determine whether MASLD progression could be represented…