A single-cell, spatial transcriptomic atlas of the Arabidopsis life cycle
A spatiotemporally resolved atlas of the Arabidopsis life cycle To generate a comprehensive atlas of Arabidopsis development, we…
In vitro evidence of bubble-induced acoustic softening and Sanal flow choking in cardiovascular decompression
This pilot in vitro study explored how decompression-induced microbubble nucleation and acoustic softening contribute to flow instability and…
Deep learning reveals antibiotics in the archaeal proteome
Deep-learning-guided identification of archaeasins We collected 18,677 non-redundant reviewed protein sequences from 233 archaeal organisms available on UniProt10…
Morphological map of under- and overexpression of genes in human cells
Mattiazzi Usaj, M. et al. High-content screening for quantitative cell biology. Trends Cell Biol. 26, 598–611 (2016). CAS …
Archived natural DNA samplers reveal four decades of biodiversity change across the tree of life
Specimen bank data This research complies with all relevant ethical regulations. All study protocols are approved by the…
The Platinum Pedigree: a long-read benchmark for genetic variants
Gonzaga-Jauregui, C., Lupski, J. R. & Gibbs, R. A. Human genome sequencing in health and disease. Annu. Rev.…
Deep-learning-based gene perturbation effect prediction does not yet outperform simple linear baselines
The success of large language models in knowledge representation has spawned efforts to apply the foundation model concept…
GeneAgent: self-verification language agent for gene-set analysis using domain databases
Model setting and data collection In this work, we utilized GPT-4 (version 20230613) as the backend model via…
Positive association between Internet use and mental health among adults aged ≥50 years in 23 countries
Global Health Data Exchange (GHDx) (Institute of Health Metrics and Evaluation, accessed 1 November 2023); https://vizhub.healthdata.org/gbd-results Mental Health…
Recognify’s Phase IIb trial of schizophrenia therapy fails to meet primary goal
atai Life Sciences (ATAI) company Recognify Life Sciences has reported that its Phase IIb trial of oral compound,…
Population-level gene copy number variations reveal distinct genetic properties of different Malus species | BMC Genomics
Weischenfeldt J, Symmons O, Spitz F, Korbel JO. Phenotypic impact of genomic structural variation: insights from and for…
Healthy Life: Ancient viruses in our DNA may hold clues to what makes us human | Healthy Life
Fragments of ancient viral DNA once dismissed as “junk” may play a role in controlling our genes, according…