CRISPR gets a power boost from AI-designed ‘molecular scissors’
An enzyme cuts DNA (artist’s impression). Synthetic protein-cleaving enzymes were designed quickly with the help of artificial intelligence.Credit:…
Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle
López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M. & Kroemer, G. The hallmarks of aging. Cell 153,…
These ‘master’ proteins protect us from deadly mutations — and could inspire new drugs
Our genomes are full of mutations that have the potential to damage our health or even kill us.…
A Surprising Discovery Suggests Autism Is Not One Condition
A major international study found evidence for two distinct autism subtypes based on how different parts of the…
Scientists Solve a 60-Year-Old Fat Cell Mystery — and It Changes What We Know About Obesity
Scientists have uncovered a surprising second role for a protein long believed to simply burn fat. The discovery…
Scientists Discover New Way To Make Drug-Resistant Cancer Treatable Again
Researchers have identified a way to weaken cancer cells by disrupting the stability of proteins responsible for repairing…
Bread Might Be Making You Gain Weight Even Without Eating More Calories
In a new study, mice strongly preferred foods like bread, rice, and wheat, abandoning their regular diet and…
De novo formation of cis-regulatory contacts in the absence of NIPBL-driven chromatin loop extrusion
Vermunt, M. W., Zhang, D. & Blobel, G. A. The interdependence of gene-regulatory elements and the 3D genome.…
This giant virus hijacks cells’ protein-making machinery to multiply wildly
Acanthamoeba polyphaga mimivirus (artist’s impression) is a giant among viruses, both in physical size and because of the…
virologist whose enzyme discovery transformed understanding of cancer and HIV/AIDS
Credit: Christopher Michel (CC-BY-SA-4.0) The world has lost a giant of virology, molecular biology and science advocacy with…
versatile gene-editing tool could tackle a host of diseases
A cell’s protein-making machinery (artist’s illustration) can be instructed to ignore mutations that would otherwise result in shortened…
Exploring the concept of bacterial memory
Richards, B. A. & Frankland, P. W. The persistence and transience of memory. Neuron 94, 1071–1084 (2017). Article …