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Browsing Tag

proteomics

22 posts
GGenetics
Investigating the role of transposable elements in shaping abdominal fat and egg production phenotypic traits in geese | BMC Genomics
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Investigating the role of transposable elements in shaping abdominal fat and egg production phenotypic traits in geese | BMC Genomics

  • September 3, 2025
Shi X, Wang J, Zeng F, Qiu X. Mitochondrial DNA cleavage patterns distinguish independent origin of Chinese domestic…
GGenetics
Imaging-based multimodal profiling of single cells with STAMP
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Imaging-based multimodal profiling of single cells with STAMP

  • August 22, 2025
Single-cell RNA sequencing (scRNA-seq) has dramatically advanced our ability to dissect complex biological systems at cellular resolution. However,…
GGenetics
Two nurses assisting an elderly woman walking
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Genetic markers could help prevent age-related frailty

  • August 8, 2025
New research links previously unknown genes to frailty, raising hope for early predicting and preventing age-related decline. Study: Large-scale…
GGenetics
Morphological map of under- and overexpression of genes in human cells
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Morphological map of under- and overexpression of genes in human cells

  • August 8, 2025
Mattiazzi Usaj, M. et al. High-content screening for quantitative cell biology. Trends Cell Biol. 26, 598–611 (2016). CAS …
GGenetics
New genetic discovery could change how Friedreich's ataxia is diagnosed
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New insights into how genes influence frailty in older adults

  • August 5, 2025
A new study has identified genetic variants linked to brain function, immune defense and metabolism that contribute to…
GGenetics
The Platinum Pedigree: a long-read benchmark for genetic variants
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The Platinum Pedigree: a long-read benchmark for genetic variants

  • August 4, 2025
Gonzaga-Jauregui, C., Lupski, J. R. & Gibbs, R. A. Human genome sequencing in health and disease. Annu. Rev.…
AArtificial intelligence
Deep-learning-based gene perturbation effect prediction does not yet outperform simple linear baselines
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Deep-learning-based gene perturbation effect prediction does not yet outperform simple linear baselines

  • August 4, 2025
The success of large language models in knowledge representation has spawned efforts to apply the foundation model concept…
GGenetics
GeneAgent: self-verification language agent for gene-set analysis using domain databases
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GeneAgent: self-verification language agent for gene-set analysis using domain databases

  • August 2, 2025
Model setting and data collection In this work, we utilized GPT-4 (version 20230613) as the backend model via…
GGenetics
Population-level gene copy number variations reveal distinct genetic properties of different Malus species | BMC Genomics
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Population-level gene copy number variations reveal distinct genetic properties of different Malus species | BMC Genomics

  • July 23, 2025
Weischenfeldt J, Symmons O, Spitz F, Korbel JO. Phenotypic impact of genomic structural variation: insights from and for…
HHealth
An AI-designed protein binder (purple and pink) envelops the flexible hormone amylin (white), preventing it from forming toxic fibrils linked to type 2 diabetes in lab tests. [Ian Haydon]
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AI Hits Disordered Proteins, Unlocks Therapy Targets

  • July 19, 2025
Drug developers have historically glued their attention to targeting the precise and fine-tuned protein structures underlying biological function.…
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