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Browsing Tag

Single-molecule biophysics

3 posts
SScience
Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity
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Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity

  • March 27, 2026
Pacesa, M., Pelea, O. & Jinek, M. Past, present, and future of CRISPR genome editing technologies. Cell 187,…
PPhysics
Quantitative evaluation of methods to analyze motion changes in single-particle experiments
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Quantitative evaluation of methods to analyze motion changes in single-particle experiments

  • July 23, 2025
Datasets and ground truth In order to benchmark the different methods on data with a known ground truth,…
PPhysics
Elastic properties of force-transmitting linkages determine multistable mechanosensitive behaviour of cell adhesion
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Elastic properties of force-transmitting linkages determine multistable mechanosensitive behaviour of cell adhesion

  • July 19, 2025
Semi-analytical mechanical model of cell-adhesion complexes To study the potential effect of the elastic properties of molecular clutches…
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