{"id":119573,"date":"2025-09-06T23:01:13","date_gmt":"2025-09-06T23:01:13","guid":{"rendered":"https:\/\/www.newsbeep.com\/uk\/119573\/"},"modified":"2025-09-06T23:01:13","modified_gmt":"2025-09-06T23:01:13","slug":"why-has-rare-appendix-cancer-quadrupled-in-millennials-aussie-professors-eye-opening-theory-as-the-dangerous-disease-sweeps-the-globe","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/uk\/119573\/","title":{"rendered":"Why has rare appendix cancer quadrupled in millennials? Aussie professor&#8217;s eye-opening theory as the dangerous disease sweeps the globe"},"content":{"rendered":"<p class=\"mol-para-with-font\">Appendix <a style=\"font-weight: bold;\" target=\"_self\" href=\"https:\/\/www.dailymail.co.uk\/news\/cancer\/index.html\" id=\"mol-781bb7b0-86f4-11f0-9cc5-dd58ed716ce6\" class=\"class\" rel=\"nofollow noopener\">cancer<\/a>\u00a0once had a reputation as one of the rarest forms of cancer.<\/p>\n<p class=\"mol-para-with-font\">Many were unaware of the condition entirely. And when doctors did encounter it, it was almost exclusively in older people&#8230; until now.<\/p>\n<p class=\"mol-para-with-font\">The number of appendix cancer cases has increased dramatically &#8211; but especially among people born after the 1970s, as documented in a <a style=\"font-weight: bold;\" class=\"class\" rel=\"noreferrer noopener nofollow\" target=\"_blank\" href=\"https:\/\/www.acpjournals.org\/doi\/10.7326\/ANNALS-24-02479\">recent study<\/a>.<\/p>\n<p class=\"mol-para-with-font\">The worrying findings noted that one in three cases of appendix cancer now occurs in adults who are under the age of 50.<\/p>\n<p class=\"mol-para-with-font\">But even though the participants were US-based, these latest results were not surprising to Australian Associate Professor, Kate Mahon, who specialises in appendiceal cancer.<\/p>\n<p class=\"mol-para-with-font\">Professor Mahon, the Director of Medical Oncology at Chris O&#8217;Brien Lifehouse at RPA in <a style=\"font-weight: bold;\" target=\"_self\" href=\"https:\/\/www.dailymail.co.uk\/news\/sydney\/index.html\" id=\"mol-782a5db0-86f4-11f0-9cc5-dd58ed716ce6\" class=\"class\" rel=\"nofollow noopener\">Sydney<\/a>,\u00a0told Daily Mail she has observed more and more younger people contracting appendix cancer Down Under too.<\/p>\n<p class=\"mol-para-with-font\">&#8216;This new study has shown that out of all cancers, the rates of gastrointestinal cancers are going up fastest,&#8217; Professor Mahon explained.\u00a0<\/p>\n<p class=\"mol-para-with-font\">&#8216;And in cancers affecting people under 50, appendix cancer is the fastest rising.&#8217;<\/p>\n<p>   <img decoding=\"async\" id=\"i-e8bf4eb08f716812\" src=\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2025\/09\/64514061-15053449-Melbourne_teacher_Kathryn_Berecic_pictured_was_diagnosed_with_ap-a-1_1756766199820.jpeg\" height=\"478\" width=\"634\" alt=\"The number of appendix cancer cases has increased dramatically. Melbourne teacher Kathryn Berecic (pictured) was diagnosed with appendix cancer at the age of 31. The news came as a complete shock as she was always 'fit and healthy'\" class=\"blkBorder img-share\" style=\"max-width:100%\" loading=\"lazy\" \/>   <\/p>\n<p class=\"imageCaption\">The number of appendix cancer cases has increased dramatically. Melbourne teacher Kathryn Berecic (pictured) was diagnosed with appendix cancer at the age of 31. The news came as a complete shock as she was always &#8216;fit and healthy&#8217;<\/p>\n<p class=\"mol-para-with-font\">&#8216;This is something we are already seeing in clinic. We&#8217;re seeing younger and younger people presenting with what used to be a much rarer cancer.<\/p>\n<p class=\"mol-para-with-font\">&#8216;And it&#8217;s not just people in their 40s, but really young patients in their 20s.&#8217;<\/p>\n<p class=\"mol-para-with-font\">THE REASON BEHIND THE RISE OF APPENDIX CANCER<\/p>\n<p class=\"mol-para-with-font\">Naturally, the question everyone wants to know is why?<\/p>\n<p class=\"mol-para-with-font\">Unfortunately, the professor says we&#8217;re currently far from pinpointing the precise reason, because it is still a &#8216;rarer&#8217; form of cancer.<\/p>\n<p class=\"mol-para-with-font\">However, because bowel cancer is also on the rise in young people &#8211; and is more prevalent than appendix cancer &#8211; Professor Mahon says some of the findings around the cause of bowel cancer offer useful &#8216;clues&#8217;\u00a0to understand appendix cancer.<\/p>\n<p class=\"mol-para-with-font\">&#8216;My gut feeling is that for appendix cancer, it has to do with the microbiome and the bugs in the bowel and the appendix,&#8217; she theorised.<\/p>\n<p class=\"mol-para-with-font\">The appendix is a small, finger-shaped pouch attached to the large intestine &#8211; with its exact purpose in the body still not entirely clear. This uncertainty only adds to the mystery of what specifically may result in cancer in this area.<\/p>\n<p>   <img decoding=\"async\" id=\"i-a60061074922d5f5\" src=\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2025\/09\/101719985-15053449-Associate_Professor_Kate_Mahon_Director_of_Medical_Oncology_at_C-a-2_175715020666.jpeg\" height=\"675\" width=\"634\" alt=\"Associate Professor Kate Mahon, Director of Medical Oncology at Chris O'Brien Lifehouse at RPA, told Daily Mail there's been a noticeable rise in appendix cancer being diagnosed among younger patients\" class=\"blkBorder img-share\" style=\"max-width:100%\" loading=\"lazy\" \/>   <\/p>\n<p class=\"imageCaption\">Associate Professor Kate Mahon, Director of Medical Oncology at Chris O&#8217;Brien Lifehouse at RPA, told Daily Mail there&#8217;s been a noticeable rise in appendix cancer being diagnosed among younger patients<\/p>\n<p class=\"mol-para-with-font\">&#8216;Although we still don&#8217;t clearly know what the purpose of the appendix is, there is a suggestion that it&#8217;s like a repository of bugs for our microbiome, of our gut,&#8217; she said.<\/p>\n<p class=\"mol-para-with-font\">&#8216;It&#8217;s like a little, a little storage of gut bugs, where they sit and wait before they populate the bowel.<\/p>\n<p class=\"mol-para-with-font\">&#8216;So it wouldn&#8217;t surprise me if [the cause of appendix cancers] is going to be related to some imbalance of the gut bugs, and having the wrong ones in there, which may come back to diet.&#8217;<\/p>\n<p class=\"mol-para-with-font\">The professor added that other potential contributors being considered are excessive intake of seed oils in processed foods, antibiotics in processed foods and even consumption of\u00a0microplastics.<\/p>\n<p class=\"mol-para-with-font\">&#8216;These are all things that researchers are going to be looking into more seriously as the numbers rise,&#8217; she said.\u00a0<\/p>\n<p> A growing thread: Appendix cancer in Australia at a glance\u00a0  <\/p>\n<p class=\"mol-para-with-font\">&#8211; Appendix cancer occurs when cells in the appendix become abnormal and continue to grow, forming a tumour<\/p>\n<p class=\"mol-para-with-font\">&#8211; The causes are unknown, and there are no clear risk factors &#8211; it also does not appear to run in families. Increasing age, however, may raise the risk of developing appendix cancer<\/p>\n<p class=\"mol-para-with-font\">&#8211; It&#8217;s a rare condition, with the most common types occurring in Australians aged between 40 and 60<\/p>\n<p class=\"mol-para-with-font\">&#8211; In 2024, an estimated 874 people were diagnosed with appendiceal cancer<\/p>\n<p class=\"mol-para-with-font\">&#8211; There is currently no screening available for appendix cancer in Australia<\/p>\n<p class=\"mol-para-with-font\">&#8211; Appendix cancer is often discovered during abdominal surgery for a different condition or after surgical removal of the appendix due to a suspected case of appendicitis<\/p>\n<p>   <img decoding=\"async\" id=\"i-4cf5cef2a8158376\" src=\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2025\/09\/101859077-15053449-image-a-2_1757044732146.jpg\" height=\"391\" width=\"586\" alt=\"Appendix cancer occurs when cells in the appendix become abnormal and continue to grow, forming a tumour\" class=\"blkBorder img-share\" style=\"max-width:100%\" loading=\"lazy\" \/>   <\/p>\n<p class=\"imageCaption\">Appendix cancer occurs when cells in the appendix become abnormal and continue to grow, forming a tumour<\/p>\n<p> &lt;!- &#8211; ad: https:\/\/mads.dailymail.co.uk\/v8\/us\/femail\/none\/article\/other\/mpu_factbox.html?id=mpu_factbox_1 &#8211; -&gt;<\/p>\n<p>Advertisement<\/p>\n<p class=\"mol-para-with-font\">DIAGNOSING APPENDIX CANCER EARLY<\/p>\n<p class=\"mol-para-with-font\">Being a rare form of cancer means there isn&#8217;t a screening program or standard test to diagnose appendix cancer.<\/p>\n<p class=\"mol-para-with-font\">In fact, the expert noted that the most common instance of appendix cancer being caught early is when it&#8217;s mistaken\u00a0for appendicitis. In those instances, the cancer is usually only diagnosed upon post-examination of the removed appendix.<\/p>\n<p class=\"mol-para-with-font\">&#8216;Unfortunately for the majority of patients, appendix cancer is only detected once it has spread into the abdominal cavity,&#8217; the professor said.<\/p>\n<p class=\"mol-para-with-font\">This is precisely what happened to Australian woman Kathryn Berecic, who <a style=\"font-weight: bold;\" target=\"_self\" class=\"class\" href=\"https:\/\/www.dailymail.co.uk\/femail\/real-life\/article-11423963\/Kathryn-Berecic-symptoms-appendix-cancer.html\" rel=\"nofollow noopener\">previously spoke to Daily Mail.<\/a><\/p>\n<p class=\"mol-para-with-font\">The Melbourne teacher was 31 years old when she went into hospital in 2021 for what she thought was routine appendix removal surgery.<\/p>\n<p class=\"mol-para-with-font\">But this operation quickly led to the discovery that she had widespread stage four appendix cancer.<\/p>\n<p>   <img decoding=\"async\" id=\"i-bd8a55a82c23a487\" src=\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2025\/09\/64514067-15053449-She_received_the_devastating_diagnosis_last_year_and_since_then_-a-2_1756766202648.jpeg\" height=\"429\" width=\"634\" alt=\"Kathryn received the devastating diagnosis in 2021 and has since undergone numerous surgeries and treatments for her stage 4 appendix cancer\" class=\"blkBorder img-share\" style=\"max-width:100%\" loading=\"lazy\" \/>   <\/p>\n<p class=\"imageCaption\">Kathryn received the devastating diagnosis in 2021 and has since undergone numerous surgeries and treatments for her stage 4 appendix cancer<\/p>\n<p class=\"mol-para-with-font\">Professor Mahon explains that unbeknownst to the patient, appendix cancer proliferates inside the tube and fills &#8216;up like a balloon&#8217;.<\/p>\n<p class=\"mol-para-with-font\">&#8216;And then it bursts out the bottom, and spreads throughout the abdominal cavity,&#8217; Professor Mahon explained.<\/p>\n<p class=\"mol-para-with-font\">&#8216;Once it&#8217;s done that, it spreads around really easily, all the way up to the liver, above the spleen, and all through the abdomen.<\/p>\n<p class=\"mol-para-with-font\">By this point, the prognosis is often that the cancer is &#8216;not curable&#8217;.\u00a0<\/p>\n<p class=\"mol-para-with-font\">Professor Mahon works out of Chris O&#8217;Brien Lifehouse, which is one of a handful of centres in Australia that offers peritonectomy surgery to treat a cancer in this abdominal region.\u00a0<\/p>\n<p class=\"mol-para-with-font\">&#8216;Beyond that big operation, we give chemo to slow it down and control it for a while,&#8217; she said.<\/p>\n<p class=\"mol-para-with-font\">&#8216;But ultimately it&#8217;s not curable, and ultimately people do die from it.&#8217;<\/p>\n<p class=\"mol-para-with-font\">THE SUBTLE EARLY SYMPTOMS OF APPENDIX CANCER<\/p>\n<p class=\"mol-para-with-font\">Although appendix cancer is difficult to detect, Professor Mahon says there are some acute symptoms to watch for, such as bloating and unexplained weight gain.<\/p>\n<p> Signs and symptoms of appendix cancer <\/p>\n<p class=\"mol-para-with-font\">Appendix cancer may not cause symptoms in its early stages. However, some people may experience symptoms such as:\u00a0<\/p>\n<p>appendicitis (lower right abdominal pain)gradual increase in waist sizebuild-up of fluid in the abdomenbloating changes in bowel habitsherniaovarian mass or lump<\/p>\n<p class=\"mol-para-with-font\">Source: <a style=\"font-weight: bold;\" class=\"class\" rel=\"noreferrer noopener nofollow\" target=\"_blank\" href=\"https:\/\/www.cancer.org.au\/cancer-information\/types-of-cancer\/rare-cancers\/appendix-cancer\">Cancer Council<\/a><\/p>\n<p> &lt;!- &#8211; ad: https:\/\/mads.dailymail.co.uk\/v8\/us\/femail\/none\/article\/other\/mpu_factbox.html?id=mpu_factbox_2 &#8211; -&gt;<\/p>\n<p>Advertisement<\/p>\n<p class=\"mol-para-with-font\">Bowel blockages are also common, and it can be accompanied by discomfort in the stomach and even vomiting.\u00a0<\/p>\n<p class=\"mol-para-with-font\">Professor Mahon encourages anyone with these type of symptoms to see their doctor and request a CT scan for closer examination of the appendix.\u00a0<\/p>\n<p class=\"mol-para-with-font\">&#8216;Doctors are far less dismissive of these things in young people after the recent rise in gastrointestinal cancers among young people,&#8217; she said.<\/p>\n<p class=\"mol-para-with-font\">PREVENTATIVE LIFESTYLE CHANGES TO MAKE NOW<\/p>\n<p class=\"mol-para-with-font\">Although the specific causes of appendix cancer remain unknown, the expert says there are lifestyle adjustments regarded as broadly beneficial for preventing a range of cancers.<\/p>\n<p class=\"mol-para-with-font\">&#8216;Eat a good balanced diet with lots of whole foods that are high in fibre, and less processed food,&#8217; she suggests.<\/p>\n<p class=\"mol-para-with-font\">&#8216;I also think prebiotics and probiotics are important &#8211; so try eating things that have cultures and have good bugs in them.<\/p>\n<p class=\"mol-para-with-font\">&#8216;And then there&#8217;s exercise. We have good evidence now about the risk of recurrence of bowel cancer being reduced by exercise,&#8217; she says, adding that the goal should be a mixture of weights and strength exercises that &#8216;really get your heart rate up&#8217;.<\/p>\n<p> How a fit 38-year-old discovered he had appendix cancer discovery\u00a0\u00a0  <\/p>\n<p class=\"mol-para-with-font\">Wylie Dixon was newly married and excited for his future when the &#8216;fit and healthy&#8217; retail manager received devastating news that he had an aggressive form of appendix cancer.<\/p>\n<p class=\"mol-para-with-font\">The then 38-year-old had been struggling with months of fatigue, but doctors dismissed the &#8216;vague&#8217; symptom so he assumed there was nothing to worry about.<\/p>\n<p class=\"mol-para-with-font\">It wasn&#8217;t until he began experiencing excruciating stomach pains and vomiting that he was rushed to the emergency room &#8211; where he learned he had stage four cancer.<\/p>\n<p class=\"mol-para-with-font\">&#8216;I was heartbroken,&#8217; Wylie, now 39, told FEMAIL.<\/p>\n<p class=\"mol-para-with-font\">&#8216;I was in disbelief as I&#8217;d never heard of the cancer before&#8230; I wasn&#8217;t someone who had scheduled health check-ups but I went to the doctor often when something would arise.<\/p>\n<p class=\"mol-para-with-font\">By the time he was diagnosed in August 2024, Wylie was told he may have just three months to live &#8211; completely turning his world upside down.<\/p>\n<p class=\"mol-para-with-font\">He explained that he just can&#8217;t fathom how his condition turned into such an extremely rare case, especially since there were no alarming symptoms before his appendix cancer diagnosis.<\/p>\n<p class=\"mol-para-with-font\">&#8216;I didn&#8217;t have any major symptoms besides fatigue. That&#8217;s the problem with this cancer, everything was vague and didn&#8217;t persist, besides the fatigue,&#8217; he said.<\/p>\n<p>   <img decoding=\"async\" id=\"i-76e82eb0fcb4ab8f\" src=\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2025\/09\/100418965-15053449-Wylie_Dixon_received_devastating_news_that_he_had_an_aggressive_-a-41_17567074191.jpeg\" height=\"674\" width=\"586\" alt=\"Wylie Dixon received devastating news that he had an aggressive form of appendix cancer\" class=\"blkBorder img-share\" style=\"max-width:100%\" loading=\"lazy\" \/>   <\/p>\n<p class=\"imageCaption\">Wylie Dixon received devastating news that he had an aggressive form of appendix cancer<\/p>\n<p class=\"mol-para-with-font\">The treatment plan saw Wylie undergo a 19-hour peritonectomy surgery, a highly invasive surgical procedure to remove the cancerous tumours from his body.<\/p>\n<p class=\"mol-para-with-font\">Since then, he has been enduring intense rounds of chemotherapy.<\/p>\n<p class=\"mol-para-with-font\">&#8216;It&#8217;s been a very long recovery from the operation, I&#8217;m still going eight months on he said in August 2025. It&#8217;s very much a watch and wait game at the moment,&#8217; he explained.<\/p>\n<p class=\"mol-para-with-font\">Despite getting the all-clear, his cancer has returned, and he&#8217;s now looking into travelling to Japan or Germany for new treatment options.<\/p>\n<p class=\"mol-para-with-font\">&#8216;The likelihood of recurrence is very high,&#8217; he explained.<\/p>\n<p class=\"mol-para-with-font\">With both Wylie and his wife unable to work, the rising cost of flights, temporary accommodation, medications, ongoing treatment, and countless specialist appointments have become overwhelming.<\/p>\n<p class=\"mol-para-with-font\">&#8216;The stress of mounting bills threatens to overshadow the one thing that matters most: Wylie&#8217;s recovery,&#8217; his cousin Ashleigh said on his GoFundMe page.<\/p>\n<p class=\"mol-para-with-font\">&#8216;We are asking for your help. Your donation, no matter the size, will help lift some of this burden &#8211; giving Wylie the chance to focus on healing without the added weight of financial stress. It will help ensure he can continue receiving the lifesaving care.<\/p>\n<p>   <img decoding=\"async\" id=\"i-43699b99f34c7160\" src=\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2025\/09\/100418953-15053449-But_his_world_came_to_a_halt_when_the_fit_and_healthy_retail_man-a-40_17567074008.jpeg\" height=\"671\" width=\"586\" alt=\"But his world came to a halt when the 'fit and healthy' retail manager received devastating news that he was living with an aggressive form of appendix cancer\" class=\"blkBorder img-share\" style=\"max-width:100%\" loading=\"lazy\" \/>   <\/p>\n<p class=\"imageCaption\">But his world came to a halt when the &#8216;fit and healthy&#8217; retail manager received devastating news that he was living with an aggressive form of appendix cancer<\/p>\n<p class=\"mol-para-with-font\">&#8216;Please consider supporting Wylie during this incredibly difficult chapter. Every dollar and every message of encouragement means more than you can imagine.&#8217;<\/p>\n<p class=\"mol-para-with-font\">By sharing his story, Wylie hopes to encourage young people to push for more answers if their symptoms are overlooked simply because they&#8217;re considered &#8216;too young to have cancer&#8217;.\u00a0<\/p>\n<p class=\"mol-para-with-font\">&#8216;I just hope there&#8217;s more awareness of appendix cancer because there is no real screening process for it,&#8217; Wylie said.<\/p>\n<p class=\"mol-para-with-font\">GPs shouldn&#8217;t dismiss symptoms just because someone is young,&#8217; Wylie said.<\/p>\n<p class=\"mol-para-with-font\">&#8216;We&#8217;re now seeing cancer rates in younger people go through the roof.&#8217;<\/p>\n<p> &lt;!- &#8211; ad: https:\/\/mads.dailymail.co.uk\/v8\/us\/femail\/none\/article\/other\/mpu_factbox.html?id=mpu_factbox_3 &#8211; -&gt;<\/p>\n<p>Advertisement<\/p>\n","protected":false},"excerpt":{"rendered":"Appendix cancer\u00a0once had a reputation as one of the rarest forms of cancer. Many were unaware of the&hellip;\n","protected":false},"author":2,"featured_media":119574,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[97,519,59,102,56,54,55],"class_list":{"0":"post-119573","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-dailymail","9":"tag-femail","10":"tag-gb","11":"tag-health","12":"tag-uk","13":"tag-united-kingdom","14":"tag-unitedkingdom"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/119573","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/comments?post=119573"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/119573\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media\/119574"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media?parent=119573"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/categories?post=119573"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/tags?post=119573"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}