{"id":123309,"date":"2025-09-08T17:37:21","date_gmt":"2025-09-08T17:37:21","guid":{"rendered":"https:\/\/www.newsbeep.com\/uk\/123309\/"},"modified":"2025-09-08T17:37:21","modified_gmt":"2025-09-08T17:37:21","slug":"crispr-used-in-landmark-treatment-to-fix-misspelling-in-babys-genome","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/uk\/123309\/","title":{"rendered":"CRISPR used in landmark treatment to fix misspelling in baby’s genome"},"content":{"rendered":"

For the first time, scientists say they have reached into the genome of a severely ill child and rewritten the unique misspelling in his DNA.\u00a0<\/p>\n

The results, published<\/a> in the New England Journal of Medicine on Thursday, are a landmark in the 50-year quest to read and repair the code of life. The boy, a now 9.5-month-old named KJ, was diagnosed days after birth with an ultra-rare disease that impairs his liver\u2019s ability to process ammonia, which can build up and cause permanent brain damage or death.\u00a0<\/p>\n

KJ had been living in the hospital, waiting until he was old enough to receive a liver transplant. Instead, at 6 months, doctors administered the first dose of the gene editing treatment. They have since been able to loosen a strict low-protein diet and reduce his daily ammonia-lowering medications by half.\u00a0<\/p>\n

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