{"id":169078,"date":"2025-09-29T22:27:06","date_gmt":"2025-09-29T22:27:06","guid":{"rendered":"https:\/\/www.newsbeep.com\/uk\/169078\/"},"modified":"2025-09-29T22:27:06","modified_gmt":"2025-09-29T22:27:06","slug":"kansas-citys-childrens-mercy-hospital-debuts-a-new-way-of-sequencing-genes-kcur","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/uk\/169078\/","title":{"rendered":"Kansas City\u2019s Children\u2019s Mercy Hospital debuts a new way of sequencing genes | KCUR"},"content":{"rendered":"<p>A decade after becoming the first clinic to offer whole genome sequencing, <a href=\"https:\/\/news.childrensmercy.org\/unlocking-answers-faster-childrens-mercy-revolutionizes--genetic-disease-diagnosis-with-a-single-test\/\" class=\"Link\" target=\"_blank\" rel=\"nofollow noopener\">Children\u2019s Mercy Hospital<\/a> in Kansas City is pioneering the use of a technology that reveals even more of a person\u2019s genome \u2014 called five-base, long-read sequencing.<\/p>\n<p>As its name suggests, this method goes beyond showing just the four DNA bases (A,G,C,T). It also reveals how cells read them and if they are used at all.<\/p>\n<p>\u201cSo we have about 10,000 rare genetic diseases, and each of those is characterized by a different problem in the genome,\u201d said Dr. Tomi Pastinen, director of the program <a href=\"https:\/\/www.childrensmercy.org\/childrens-mercy-research-institute\/studies-and-trials\/genomic-answers-for-kids\/\" class=\"Link\" target=\"_blank\" rel=\"nofollow noopener\">Genomic Answers for Kids<\/a>. \u201cA single letter changed among the 6 billion letters in your genome can lead to a devastating disease and early death, even in the worst case scenario.\u201d<\/p>\n<p>Pastinen led the first clinical study of five-base, long-read sequencing, which was published this month in the <a href=\"https:\/\/jamanetwork.com\/journals\/jamapediatrics\/fullarticle\/2838675?resultClick=1\" class=\"Link\" target=\"_blank\" rel=\"nofollow noopener\">Journal of the American Medical Association Pediatrics<\/a>.<\/p>\n<p>With this new technology, clinicians can cut years off the waiting time for a diagnosis and get results in as little as four weeks.<\/p>\n<p>Children\u2019s Mercy is currently the only clinic offering this testing and receives patients from all over the country.<\/p>\n","protected":false},"excerpt":{"rendered":"A decade after becoming the first clinic to offer whole genome sequencing, Children\u2019s Mercy Hospital in Kansas City&hellip;\n","protected":false},"author":2,"featured_media":169079,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[916,90,56,54,55],"class_list":["post-169078","post","type-post","status-publish","format-standard","has-post-thumbnail","category-genetics","tag-genetics","tag-science","tag-uk","tag-united-kingdom","tag-unitedkingdom"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/169078","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/comments?post=169078"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/169078\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media\/169079"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media?parent=169078"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/categories?post=169078"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/tags?post=169078"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}