{"id":182227,"date":"2025-10-06T20:10:10","date_gmt":"2025-10-06T20:10:10","guid":{"rendered":"https:\/\/www.newsbeep.com\/uk\/182227\/"},"modified":"2025-10-06T20:10:10","modified_gmt":"2025-10-06T20:10:10","slug":"revealed-which-slimming-jab-really-works-best-the-doctors-ultimate-expert-guide-on-which-to-pick-how-to-save-money-beat-every-side-effect-and-what-you-need-to-know-about-the-golden-dose","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/uk\/182227\/","title":{"rendered":"Revealed: Which slimming jab REALLY works best. The doctors’ ultimate expert guide on which to pick, how to save money, beat every side effect… and what you need to know about the ‘golden dose’"},"content":{"rendered":"

They\u2019re the medical revolution of this century, drugs that help you lose weight<\/a> without a huge amount of effort.<\/p>\n

First there were Victoza and Saxenda, then Ozempic seized the spotlight \u2013 followed by Wegovy and Mounjaro.<\/p>\n

And the range is rapidly expanding \u2013 there are now tens of weight-loss drugs under development, with ever-better products promised soon.<\/p>\n

CagriSema is soon to be the new drug on the block, promising the most weight loss yet \u2013 up to 23 per cent of body weight a year, compared with 16 per cent with Wegovy and 22 per cent with Mounjaro.<\/p>\n

It combines semaglutide \u2013 the active ingredient also in Wegovy and Ozempic, which mimics glucagon-like peptide-1 (GLP-1), a key hormone produced by the intestine after you have eaten \u2013 with a new molecule called cagrilintide, which mimics the hormone amylin, which slows your stomach emptying, making you feel full for longer after eating. CagriSema is due to become available next year.<\/p>\n

Similar results have been seen with retatrutide, developed by Eli Lilly, the maker of Mounjaro. In just 24 weeks, patients lost an average 24 per cent of body weight. Also known as \u2018Triple G\u2019, it targets GLP-1 and two other appetite hormones \u2013 GIP and glucagon \u2013 \u2018increasing the efficacy of the medications\u2019, says Alex Miras, a clinical professor of medicine at Ulster University. And there may soon be a more appealing option, a daily pill that\u2019s also cheaper than weekly jabs.<\/p>\n

There\u2019s no doubt these types of drugs, which have been around for nearly 20 years to treat type 2 diabetes, can be game-changers for those with severe obesity.<\/p>\n

As Carel Le Roux, a professor of metabolic medicine at Ulster University, explains: \u2018The benefits may go beyond short-term weight loss, they may also improve heart health, combat kidney disease and lower the risk of dementia.<\/p>\n

\"Weight-loss <\/p>\n

Weight-loss jabs work by mimicking a natural ‘fullness’ hormone and slowing down digestion, but many report some unwelcome side-effects<\/p>\n

\"Carel <\/p>\n

Carel Le Roux highlights the life-changing benefits of weight-loss jabs<\/p>\n

\u2018This is because the drugs reduce fat that causes problems inside specific organs, but also because the drugs have benefits beyond weight loss.\u2019<\/p>\n

He adds: \u2018Some people are able to function in a way they haven\u2019t for years: to do up their laces, to walk to the shops, to go back to work.\u2019<\/p>\n

Other benefits include cutting your desire for alcohol \u2013 \u2018semaglutide dampens down the brain\u2019s reward system, resulting in individuals no longer getting the same pleasure from drinking,\u2019 explains Dr Mamta Joshi, an endocrinologist at Epsom and St Helier University Hospitals NHS Trust.<\/p>\n

It can have the same effect on your desire to smoke.<\/p>\n

But the new weight-loss jabs aren\u2019t without risk, with potential side-effects ranging from the mild, such as nausea, diarrhoea and rotten egg burps (as the stomach empties more slowly, food remains there longer and can ferment, leading to a build-up of stinky hydrogen sulphide gas).<\/p>\n

People have also reported worrying cosmetic changes such as \u2018Ozempic face\u2019, \u2018Ozempic teeth\u2019, even \u2018Ozempic vagina\u2019.<\/a> Plus, there\u2019s a risk of pancreatitis (an inflamed pancreas), hospitalisation and, though much more rarely, death: last year tirzepatide (the active ingredient in Mounjaro) was recorded as a contributing factor in the death of Susan McGowan, a 58-year-old nurse from North Lanarkshire.<\/p>\n

\u2018Such extreme side-effects are rare, but people need to be aware that these drugs aren\u2019t a quick-fix for someone who just wants to lose a few pounds \u2013 they should only be taken under medical supervision,\u2019 says Dr Foteini Kavvoura, a consultant endocrinologist at the Royal Berkshire NHS Foundation Trust.<\/p>\n

But with strict criteria for accessing these drugs on the NHS<\/a>, many people are buying the drugs online \u2013 with no guarantee you\u2019re getting the real drug. There have been reports of people in the UK needing hospital treatment after buying what turned out to be fake semaglutide from a hairdresser or \u2018a friend of a friend\u2019.<\/p>\n

So how do you navigate the minefield of options? What can you do to avoid the side-effects? Plus, how soon are the new, even better jabs going to become available? We spoke to the experts to find out\u2026<\/p>\n

\u00a0HOW CAN I GET THE JABS?<\/p>\n

There\u2019s no doubt lots of people would like to be on weight-loss jabs \u2013 around one in five Britons has tried to get hold of weight-loss drugs over the past year, rising to one in three among 18 to 34-year-olds<\/a>.<\/p>\n

But the cost can be prohibitive, from between \u00a399 to \u00a3370 for a month\u2019s supply.<\/p>\n

Add to this Eli Lilly\u2019s recent announcement that it was upping its wholesale prices by more than 170 per cent \u2013 though it\u2019s since been reported that the company is trying to reduce this \u2013 experts now fear the market could be flooded with fake drugs.<\/p>\n

GETTING THEM ON THE NHS: To get them free on the NHS you have to meet strict criteria to be considered (and even then you may struggle).<\/p>\n

For semaglutide (Wegovy), you need to have a BMI of 30 and over, and to have at least one weight-related medical condition such as high blood pressure or sleep apnoea. The BMI is lower (27.5) for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African Caribbean family backgrounds because of their increased risk of weight-related disease at lower body weights.<\/p>\n

Tirzepatide (Mounjaro), which was only authorised for prescription on the NHS in June, has different criteria \u2018due to the large number of patients qualifying and its high cost\u2019, explains Dr Kavvoura. There is a three-year roll-out programme, prioritising those with highest clinical need: currently you need to have a BMI of 40 and over, with at least four of the following five weight-related medical conditions: type 2 diabetes, high blood pressure, sleep apnoea, high cholesterol or cardiovascular disease. For the higher-risk ethnic groups, it\u2019s a BMI of 37.5. The second phase of the roll-out is planned for June 2026 and expected to include patients with a BMI of 35 and over (32.5 for ethnic groups), plus the weight-related conditions.<\/p>\n

Your browser does not support iframes.<\/p>\n

GETTING THEM PRIVATELY: The criteria are less strict, as it\u2019s according to the drug\u2019s licence rather than NHS rules \u2013 under the licence you can get them if your BMI is 27 and over, and you have at least one obesity-related complication, or simply if your BMI is more than 30.<\/p>\n

This applies to all medications licensed for obesity, including liraglutide (Saxenda), semaglutide and tirzepatide, says Professor Miras.<\/p>\n

While some people are getting semaglutide in the form of Ozempic for obesity, it\u2019s actually only licensed for type 2 diabetes<\/a>, so is being prescribed off-label \u2013 here, the prescriber bears more responsibility should things go wrong.<\/p>\n

FROM AN ONLINE PHARMACY: To protect yourself you should only buy from a UK pharmacy that\u2019s registered with the General Pharmaceutical Council (GphC), says Laura Wilson, director of the Royal Pharmaceutical Society in Scotland.<\/p>\n

This guarantees you\u2019re receiving safe, regulated care. Some illegitimate websites look hugely convincing, so to check, click on the green cross pharmacy logo on the website and you\u2019ll be taken through to the GPhC register, confirming it\u2019s legitimate.<\/p>\n

You can also search the website pharmacyregulation.org \u2013 which lists every registered pharmacy in the UK.<\/p>\n

\u2018If you don\u2019t need a prescription, there\u2019s no address or number, or if the deal looks too good to be true \u2013 avoid it,\u2019 says Laura Wilson.<\/p>\n

A responsible pharmacy will ask for detailed health information such as your medical history and current medications, confirm your identity and have all this reviewed by doctors. They\u2019ll also provide ongoing support, including how to use the medicine safely and possible side-effects.<\/p>\n

Expect to pay between \u00a390 and \u00a3370 for a month\u2019s supply.<\/p>\n

FROM A PRIVATE CLINIC: If you\u2019re getting the drug through a private clinic the support you get should be comprehensive \u2013 including initial assessments, ongoing monitoring plus customised nutrition, exercise and lifestyle advice.<\/p>\n

Check the clinic is registered with the Care Quality Commission: cqc.org.uk. This means it meets essential safety and quality standards.<\/p>\n

\u2018If it\u2019s not registered, you\u2019ve no idea what you\u2019re getting,\u2019 adds Laura Wilson.<\/p>\n

\u2018You could get something that doesn\u2019t work at all or, worse, something containing toxins and other ingredients that could cause real harm \u2013 you may even end up in hospital.\u2019<\/p>\n

Expect to pay from \u00a3400 for initial consultations with a GP and a dietitian; between \u00a3169 and \u00a3375 per month for the medication; and from \u00a3170 for follow-up appointments with a GP and dietitian.<\/p>\n

WHEN WILL I START TO LOSE WEIGHT?<\/p>\n

You could start to see results almost within days, although not everyone will (see below).<\/p>\n

\u2018The mechanism behind all of these drugs is simple,\u2019 says Professor Le Roux, \u2018they make you feel fuller for longer and reduce your appetite\u2019.<\/p>\n

\"The <\/p>\n

The prospect of a pill rather than a jab will appeal to many looking for weight-loss solutions\u00a0<\/p>\n

They work by mimicking GLP-1. This hormone stimulates insulin secretion and slows down the rate food is digested. This in turn acts in the brain on the reward system to reduce hunger and to signal feelings of fullness.<\/p>\n

\u2018It doesn\u2019t change the appeal of food, just the intense desire for it; as patients say, it quietens \u201cfood noise\u201d,\u2019 adds Professor Le Roux.<\/p>\n

Because of this you eat less \u2013 calorie intake can drop by 70 per cent for the first few months, then levels out to 30 per cent from six months.<\/p>\n

However, this can mean you miss out on important nutrients, and protein (more on protein later).<\/p>\n

The food industry is now starting to market ranges of foods specifically designed to \u2018complement\u2019 these drugs.<\/p>\n

Last year, Nestle became the first major food company to launch an entirely new brand, Vital Pursuit, targeted specifically at patients on semaglutide.<\/p>\n

The range, currently only available in the US, is designed to provide \u2018dietary support to GLP-1 users and consumers focused on weight management\u2019 and features frozen meals such as cauliflower crust three-meat pizza, and chicken spinach and artichoke sandwich melt. All meals contain at least 20g of protein.<\/p>\n

In addition, in June this year it launched \u2018Boost Advanced\u2019 \u2013 shakes said to \u2018meet science-based nutritional recommendations for users of GLP-1 receptor agonists\u2019. They contain 35g of protein to help \u2018preserve muscles during weight loss, along with a special blend of nutrients designed to support digestive health and energy metabolism\u2019.<\/p>\n

HOW CAN I TELL IT\u2019S\u00a0NOT\u00a0GOING TO WORK FOR ME?<\/p>\n

Although the drugs can work for large numbers of people, they don\u2019t work for some.<\/p>\n

If the weight loss is less than 5 per cent after three months, you\u2019re known as a \u2018non-responder\u2019, which accounts for about 5 to 8 per cent of people, says Professor Le Roux.<\/p>\n

Why this happens isn\u2019t clear, adds Professor Miras. \u2018We suspect it has to do with the way the drug interacts with the GLP-1 receptor in the brain \u2013 i.e. how well the key interacts with the lock. If the key enters the lock well then we have a good result and the other way round.\u2019<\/p>\n

Professor Le Roux adds: \u2018We have zero ability to predict who will fall into this camp.\u2019<\/p>\n

CAN I AVOID THE SIDE-EFFECTS?<\/p>\n

\u2018OZEMPIC FACE\u2019<\/p>\n

While the weight loss may be welcome, gaunt, sallow-looking skin is less so. Known as \u2018Ozempic face\u2019 this is actually nothing to do with the medication and \u2018all to do with the rapid weight loss\u2019, says Dr Sharon Wong, a dermatologist in London and spokeswoman for the British Association of Dermatologists.<\/p>\n

\u2018The loss of fat and collagen in the skin \u2013 and elasticity \u2013 results in a more sunken appearance, with noticeable sagging and wrinkles. This is a particularly common side-effect when people maximise their dose in an effort to achieve weight goals quickly \u2013 however the faster you do this, the more likely the so-called Ozempic face will appear,\u2019 she adds.<\/p>\n

\u2018To minimise the loss, lose weight gradually \u2013 ideally 1-2lb per week; this gives skin time to adapt, protects muscle and reduces the risk of sagging,\u2019 says Charlotte Foster, a dietitian at Barts NHS Trust.<\/p>\n

Your diet is also important, as your appetite is reduced, you need to ensure that what you do eat is nutrient dense, such as fruits, vegetables, wholegrains, oily fish, beans and lentils, she explains.<\/p>\n

\u2018Keep hydrated, too. Water is vital for skin elasticity, digestion, energy and overall health.\u2019<\/p>\n

London-based dietitian Emer Delaney adds: \u2018Most important is protein \u2013 aim for around 1-1.5g per kg body weight per day.\u2019<\/p>\n

LOSING TOO MUCH MUSCLE<\/p>\n

A significant amount of the weight you lose is muscle \u2013 not fat. This is important as muscles burn calories when you\u2019re at rest, too.<\/p>\n

Muscle loss with GLP-1 drugs ranges from 25 per cent to 39 per cent of the total weight lost over 36-72 weeks, reported The Lancet Diabetes & Endocrinology journal last year. This is several times greater than muscle loss you\u2019d expect through simple ageing past 40.<\/p>\n

\u2018The reduced diet and nutrients mean muscle proteins break down faster than they can be built,\u2019 says Dr Kavvoura.<\/p>\n

\u2018It has a knock-on effect on bones too; when weight loss is extreme and quick, we lose fat from inside our bones, just in the same way we lose fat from other areas.\u2019<\/p>\n

Muscle mass is not only vital for your metabolism \u2013 but also for muscle strength and independence, particularly as we age.<\/p>\n

To minimise the loss, make sure you eat plenty of protein.<\/p>\n

\u2018As well as meat, good sources of protein include eggs, beans, seafood, cheese, peas and nuts,\u2019 says Emer Delaney.<\/p>\n

\u2018The calorie restriction can make it difficult to consume the ideal amount so adding additional protein powder to a small pot of high-protein yoghurt \u2013 can really help.\u2019<\/p>\n

Professor Le Roux adds: \u2018Muscle loss can also be limited by exercise \u2013 particularly important in those over the age of 50, when you\u2019re losing muscle anyway.<\/p>\n

\u2018Resistance training such as squats, lunges, weight-lifting \u2013 even lifting water bottles in each arm \u2013 can help.\u2019<\/p>\n

‘OZEMPIC VAGINA’<\/p>\n

That gaunt, saggy-skinned look that affects the face, can also affect the labia or vagina as a result of rapid weight loss. \u2018Rapid weight loss on any body part can affect the skin over the fatty tissue lost \u2013 including the lower belly, mons pubis, and inner and outer labia,\u2019 says Dr Sherry Ross, an associate professor of urology at the University of North Carolina.<\/p>\n

While anyone can be affected by it, those more prone to the condition tend to be older women, whose skin has already lost its elasticity.<\/p>\n

PANCREATITIS<\/p>\n

Clinical trials have shown users of GLP-1 drugs have a higher risk of pancreatitis \u2013 inflammation of the pancreas \u2013 possibly due to an overgrowth of cells in the pancreas.<\/p>\n

\u2018Pancreatic inflammation is dangerous because the inflammatory process can cause complications such as cell death in the pancreas itself, potentially leading to sepsis and even death,\u2019 says Dr Christian Macutkiewicz, a consultant general and hepato-pancreatico-biliary surgeon at Manchester Royal Infirmary.<\/p>\n

\u2018Seek urgent medical attention if you have sudden severe and constant pain in your stomach area with or without vomiting,\u2019 adds Dr Kavvoura.<\/p>\n

Your browser does not support iframes.<\/p>\n

GALLSTONES<\/p>\n

Any rapid weight loss can increase the risk of gallstone as the liver secretes more cholesterol into the bile, which can crystallise into gallstones.<\/p>\n

A 2022 review in the Journal JAMA Internal Medicine found that using GLP-1s increased the risk of gallstones, particularly when used for longer durations (26 weeks or more) at higher doses (1mg or more of semaglutide once a week) and purely for weight loss.<\/p>\n

PARALYSED GUT<\/p>\n

Using GLP-1s increase the risk of paralysed gut and symptoms such as vomiting, nausea and pain, reported the journal Pharmaceuticals in 2024. The research showed that liraglutide (Victoza and Saxenda) had higher odds of gastroparesis than semaglutide. The condition is reversible once you stop taking the drug.<\/p>\n

HAIR LOSS<\/p>\n

\u2018While it\u2019s not listed as a side-effect of weight-loss medications, I see an increasing number of people attending my clinic with hair shedding or thinning after using them,\u2019 says Dr Wong.<\/p>\n

This is possibly caused by the dramatic weight loss \u2013 once the weight is stabilised and your diet has the optimum nutrients \u2013 the hair shedding should gradually settle back to normal.<\/p>\n

\u2018However, some experience hair loss without the extreme and rapid weight loss, suggesting there could be other mechanisms involved \u2013 such as a direct effect on hair follicle function,\u2019 adds Dr Wong. \u2018As an increasingly encountered problem, it\u2019s an area that requires more research.\u2019<\/p>\n

DEPRESSION\/SUICIDAL THOUGHTS<\/p>\n

A study in Nature last year found there was 195 per cent higher risk of depression and a 106 per cent increased risk of suicidal behaviour in people taking GLP-1s \u2013 based on analysis of data from more than 162,000 people.<\/p>\n

The Medicines and Healthcare products Regulatory Agency, the UK drugs watchdog, concluded that there is no causal link between these medications and depression.<\/p>\n

However, Professor Le Roux explains that while the drug itself will assist with physical weight loss, there\u2019s no evidence it will improve mood or how you feel about yourself, so people shouldn\u2019t take it in the belief it will.<\/p>\n

\u2018GLP-1s must be taken under medical supervision,\u2019 he adds, \u2018so their patient\u2019s medical history can be assessed before taking the drug\u2019.<\/p>\n

‘OZEMPIC TEETH’<\/p>\n

There are anecdotal reports of increasing numbers of people visiting their dentist with a range of oral side-effects including tooth decay, inflamed gums and dry mouth after using weight-loss jabs; it\u2019s thought the drugs could lead to an environment such as dry mouth that speeds up decay.<\/p>\n

Vomiting, another side-effect of the drugs, could erode the enamel, explains Mervyn Druian, a dentist at the London Centre for Cosmetic Dentistry.<\/p>\n

WHAT HAPPENS WHEN YOU STOP TAKING THE JABS?<\/p>\n

\"Dr <\/p>\n

Dr Mamta Joshi warns against assuming that weight will stay off<\/p>\n

As with all diets, there comes a point where you stop losing weight \u2013 and you plateau. With weight-loss drugs, this usually occurs around 72 weeks of starting them, says Dr Kavvoura.<\/p>\n

The body has achieved a new metabolic \u2018set point\u2019, explains Dr Mamta Joshi, an endocrinologist at Epsom and St Helier University Hospitals NHS Trust.<\/p>\n

\u2018It\u2019s at this point that people often come off the drugs, thinking they\u2019ve lost the weight they need to and that drugs are no longer helping them lose more weight and thus are not necessary,\u2019 explains Professor Le Roux.<\/p>\n

\u2018However, the main problem with diets is that once people stop doing them, they tend to regain weight \u2013 and weight-loss drugs are no different.\u2019<\/p>\n

In an analysis of studies on both old and new GLP-1 medications earlier this year, researchers at the University of Oxford found that patients typically lost 8kg on weight-loss medication but returned to their original weight within ten months of stopping them.<\/p>\n

There are some people who have dramatically changed their lifestyle through diet and exercise and manage to keep the weight off, but this is only around 2 to 5 per cent of people.<\/p>\n

For everyone else, the weight-loss drugs are nothing more than brakes on the appetite centre and once they\u2019ve been removed a decent amount of weight will return if alternative strategies are not put in place, says Dr Joshi.<\/p>\n

SO WHY CAN\u2019T I STAY ON THEM FOR EVER?<\/p>\n

On the NHS, semaglutide (Wegovy) is prescribed for a maximum of two years only for weight loss; this is based on NICE recommendations and certainly due to cost implications, says Dr Joshi.<\/p>\n

This two-year cap currently doesn\u2019t apply to Mounjaro, but guidelines may change as data evolves. Privately, these drugs aren\u2019t bound by these restrictions.<\/p>\n

\u2018In coming years, if we are able to demonstrate no significant increase in risk of pancreatitis events and thyroid cancer then it\u2019s likely we\u2019ll be more relaxed about using GLP-1 drugs for longer periods,\u2019 adds Dr Joshi.<\/p>\n

CAN I MICRODOSE TO SAVE MONEY AND REDUCE SIDE-EFFECTS?<\/p>\n

\u2018Microdosing\u2019 \u2013 taking smaller doses of the medications than prescribed \u2013 has become increasingly popular, particularly in the US, where the cost of the new GLP-1 drugs is much higher than in the UK.<\/p>\n

\u2018The main reason people do it is to save money, although some do it to lessen side-effects,\u2019 says Professor Miras.<\/p>\n

Others are also doing it to take that edge off hunger pangs and to lose smaller amounts, 5-10kg, of weight, too.<\/p>\n

Essentially when you administer the jab you first attach the needle to a \u2018pen\u2019 cartridge containing the drug \u2013 you then turn the dose knob on the pen to obtain the dose amount (viewable in the dose counter window) \u2013 with microdosing you would turn the knob fewer times to administer 1mg instead of a standard starting dose of 2.5mg. Or you would inject less frequently than advised, so every two weeks instead of every week, explains Professor Miras.<\/p>\n

However, using the drugs this way is off-label, meaning different from its intended use.<\/p>\n

\u2018While it\u2019s generally safe and already practised in some private clinics in the UK \u2013 there have been no clinical trials that have tried it in real patients,\u2019 he adds.<\/p>\n

\u2018Microdosing for reduced side-effects such as nausea does make some sense but shouldn\u2019t be necessary on the lowest starting doses \u2013 and for losing weight, we know from the research that it\u2019s dose dependent; the higher the dose the higher the weight loss with all the medications,\u2019 says Professor Miras<\/p>\n

\u2018It makes no sense to take lower doses because you will lose less weight. It is as simple as that.\u2019<\/p>\n

HOW ABOUT THE ‘GOLDEN DOSE’?<\/p>\n

After the four weekly doses a pen contains are used up, there is likely to be some liquid left. Some influencers have taken to calling this a fifth dose or the ‘golden dose’. But doctors warn against treating it like a bonus jab as it is at best potentially ineffective – at worst unsafe. The overfill is deliberate to ensure four full doses, but the extra is not clinically recommended as medication.<\/p>\n

P.S. EVEN BETTER JABS \u2013 OR A DAILY PILL \u2013 ARE JUST AROUND THE CORNER<\/p>\n

The next generation of weight-loss drugs look to deliver even more weight loss in safer ways \u2013 and with longer-lasting effects, says Professor Le Roux.<\/p>\n

The newest drug on the block is likely to be CagriSema, and then retatrutide.<\/p>\n

But the next big blockbuster could be MariTide, developed by Amgen, a once monthly jab (rather than weekly).<\/p>\n

Like Mounjaro, MariTide targets the hormone receptors GLP-1, but unlike Mounjaro it blocks GIP.<\/p>\n

Results of a trial published in June in the New England Journal of Medicine showed people lost up to 20 per cent weight loss in 52 weeks; significantly, many participants maintained the weight loss for six months after stopping taking it (with semaglutide, studies show patients regain an average two thirds of their weight loss within just 12 months). It could be available in 2028.<\/p>\n

Another option coming soon could be weight-loss pills targeting the same hormones.<\/p>\n

As Professor Miras explains: \u2018Oral formulations are generally more acceptable by patients even if taken daily.\u2019 These are also expected to be cheaper, although the results aren\u2019t quite as impressive as the jab.<\/p>\n

Orgorglipron, a daily pill that works like semaglutide, has just been shown to help participants lose 20 per cent of more of their body weight over 72 weeks, reported the New England Journal of Medicine. It\u2019s expected to become available in the UK in 2026.<\/p>\n","protected":false},"excerpt":{"rendered":"They\u2019re the medical revolution of this century, drugs that help you lose weight without a huge amount of…\n","protected":false},"author":2,"featured_media":182228,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[97,59,102,578,56,54,55],"class_list":{"0":"post-182227","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-dailymail","9":"tag-gb","10":"tag-health","11":"tag-ozempic","12":"tag-uk","13":"tag-united-kingdom","14":"tag-unitedkingdom"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/182227","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/comments?post=182227"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/182227\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media\/182228"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media?parent=182227"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/categories?post=182227"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/tags?post=182227"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}