{"id":325097,"date":"2025-12-19T18:31:22","date_gmt":"2025-12-19T18:31:22","guid":{"rendered":"https:\/\/www.newsbeep.com\/uk\/325097\/"},"modified":"2025-12-19T18:31:22","modified_gmt":"2025-12-19T18:31:22","slug":"what-your-mouth-can-reveal-about-your-health","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/uk\/325097\/","title":{"rendered":"What your mouth can reveal about your health"},"content":{"rendered":"<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">\u201cThe bacteria that live on your teeth are pretty much entirely different from the bacteria that live on your tongue,\u201d says <a class=\"zZygg UbGlr iFzkS qdXbA WCDhQ DbOXS tqUtK GpWVU iJYzE \" data-testid=\"prism-linkbase\" href=\"https:\/\/forsyth.org\/team_member\/jessica-mark-welch-phd\/\" target=\"_blank\" dir=\"ltr\" rel=\"nofollow noopener\">Jessica Mark Welch<\/a>, a biologist at the ADA Forsyth Institute who specializes in the oral microbiome. \u201cAnd there\u2019s a different group of bacteria on the roof of your mouth and on your gums.\u201d<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">In people with good oral health, the microbiome has a diverse community of beneficial microbes, including Streptococcus and Rothia, which help control inflammation and fend off pathogens. But that balance is sensitive. Changes in diet, oral hygiene, or overall health can quickly shift the microbial mix.<\/p>\n<p><a class=\"zZygg UbGlr iFzkS qdXbA hsDdd cBQOR tqUtK GpWVU iJYzE GpQCA lZur BOsoU YMZw dihEb srtah LmIPo JzlZQ VbrfA zZsl kjmkg OwbFk QuuaM tOHqz GfDiz rCJMb HxCWP \" data-testid=\"prism-linkbase\" href=\"https:\/\/www.nationalgeographic.com\/subscribe\/topic\/give-a-gift?cmpid=int_org=ngp::int_mc=website::int_src=ngp::int_cmp=holiday2025::int_add=articlepromo-lastchance\" aria-label=\"Last Chance - Save up to $20!\" aria-describedby=\"\" target=\"_self\" rel=\"nofollow noopener\"><img decoding=\"async\" alt=\"\" class=\"hsDdd NDJZt sJeUN IJwXl \" data-testid=\"prism-image\" draggable=\"false\" src=\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2025\/12\/NGM-All-Titles-ARTICLE-PROMO-15215_600x4001_3x2.jpg\"\/><\/a><\/p>\n<p>Last Chance &#8211; Save up to $20!<\/p>\n<p>PLUS, for a limited time, get bonus gifts and issues with all Nat Geo subscriptions.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">\u201cBacteria always respond to their environment,\u201d Mark Welch explains. \u201cIf the mouth is exposed to a lot of sugar, then bacteria that thrive on simple sugars become more abundant.\u201d<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">One of the best-known culprits is Porphyromonas gingivalis, a bacterium closely linked to periodontal, or gum, disease. While most bacteria prefer carbohydrates, P. gingivalis thrives on protein\u2014quite literally feeding on gum tissue.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">The recent JAMA Oncology study found that P. gingivalis and two other periodontal pathogens, E. nodatum and P. micra, as well as the common oral fungus Candida, were associated with a heightened risk of pancreatic cancer.<\/p>\n<p><img decoding=\"async\" alt=\"Oral bacteria. Colored scanning electron micrograph (SEM) of mixed oral bacteria attached to buccal cells (brown) from the cheek.\" class=\"hsDdd NDJZt sJeUN IJwXl vBqtr KrDt itslR zFTjo hakZw HlUVI UbGlr \" data-testid=\"prism-image\" draggable=\"false\" src=\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2025\/12\/C0293249-Oral_bacteria_SEM.jpg\"\/><\/p>\n<p>In this colored scanning electron micrograph (SEM), mixed oral bacteria adhere to buccal cells from the cheek. Researchers are increasingly exploring how these microbes influence health beyond the mouth.<\/p>\n<p>Steve Gschmeissner, Science Photo Library<\/p>\n<p>The mouth\u2013body connection<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">Chronic inflammation is a well-established risk factor for cardiovascular disease, type 2 diabetes, several cancers, and Alzheimer\u2019s disease.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">People with periodontal disease are three to five times more likely to develop cancers linked to the oral microbiome. \u201cThe hypothesis is that they develop a pathogenic type of inflammation rather than a healthy one,\u201d Freire says.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">Blood vessels under the tongue, cheeks, and other oral sites allow bacteria to migrate through the body, Freire adds. The immune system typically intercepts these bacteria, but some slip through, potentially leading to disease.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">Fusobacterium nucleatum, which is typically found in the mouth, is an example of a pathogen that can promote tumor growth through migration. Patients with colorectal cancer were five times more likely to carry F. nucleatum in their stool than healthy counterparts, according to <a class=\"zZygg UbGlr iFzkS qdXbA WCDhQ DbOXS tqUtK GpWVU iJYzE \" data-testid=\"prism-linkbase\" href=\"https:\/\/www.cancer.gov\/news-events\/cancer-currents-blog\/2024\/colorectal-cancer-fna-c2-bacteria\" target=\"_blank\" dir=\"ltr\" rel=\"nofollow noopener\">research from the National Cancer Institute<\/a>.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">Saliva offers another pathway for bacteria to travel through the digestive tract. In animal studies, P. gingivalis that migrated from the mouth has been shown to cause pancreatic cancer, according to a 2024 <a class=\"zZygg UbGlr iFzkS qdXbA WCDhQ DbOXS tqUtK GpWVU iJYzE \" data-testid=\"prism-linkbase\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38233197\/\" target=\"_blank\" dir=\"ltr\" rel=\"nofollow noopener\">study<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"\u201cThe bacteria that live on your teeth are pretty much entirely different from the bacteria that live on&hellip;\n","protected":false},"author":2,"featured_media":325098,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[59,102,127712,127711,79619,127713,56,54,55],"class_list":["post-325097","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-gb","tag-health","tag-oral-health-and-systemic-disease","tag-oral-microbiome","tag-pancreatic-cancer-risk","tag-periodontal-disease","tag-uk","tag-united-kingdom","tag-unitedkingdom"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/325097","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/comments?post=325097"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/325097\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media\/325098"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media?parent=325097"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/categories?post=325097"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/tags?post=325097"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}