{"id":395366,"date":"2026-01-28T17:34:07","date_gmt":"2026-01-28T17:34:07","guid":{"rendered":"https:\/\/www.newsbeep.com\/uk\/395366\/"},"modified":"2026-01-28T17:34:07","modified_gmt":"2026-01-28T17:34:07","slug":"ai-model-from-google-deepmind-reads-recipe-for-life-in-our-dna","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/uk\/395366\/","title":{"rendered":"AI model from Google DeepMind reads recipe for life in our DNA"},"content":{"rendered":"

Latysheva said she was “really excited” by the AI model’s potential to understand which mutations cause disease and help pinpoint the cause of rare genetic diseases.<\/p>\n

The AI model could be used to “add another piece of the puzzle for the discovery of drug targets and ultimately the development of new drugs”, she added.<\/p>\n

Ultimately, it could also be used in synthetic biology and the design of new sequences of DNA which could be used in gene therapies.<\/p>\n

AlphaGenome has been described in the journal Nature, external<\/a>, but was made available for non-commercial use last year and 3,000 scientists have since used the tool.<\/p>\n

Dr Gareth Hawkes, from the University of Exeter, is using it to explore how mutations could be altering our risk of obesity and diabetes.<\/p>\n

Studies that sequenced the entire genetic code of tens of thousands of people have identified variants linked to the conditions, but they are often in the dark genome.<\/p>\n

“They’re directly impacting some important piece of biology that we don’t really understand,” Hawkes told the BBC.<\/p>\n

Using AlphaGenome allows researchers to rapidly predict what those variants are up to so they can be tested in the lab.<\/p>\n

Hawkes said: “Those predictions will help to inform which biological processes those genetic variants might be impacting, and potentially lead to drug developments.<\/p>\n

“I wouldn’t say the dark side of the genome is solved by AlphaGenome, but it’s a big leap. I’m really excited.”<\/p>\n

Cancer is another field where the AI model could accelerate research.<\/p>\n

AlphaGenome has been used to predict which mutations are fuelling cancer and are also the potential targets of treatment, and which mutations are incidental.<\/p>\n

Dr Robert Goldstone, head of genomics at the Francis Crick Institute, said the model was a “major milestone in the field of genomic AI” and the breakthrough was “an incredible technical feat” for its “ability to predict gene expression from DNA sequence alone”.<\/p>\n

Prof Ben Lehner, the head of generative and synthetic genomics at the Wellcome Sanger Institute, said they had tested AlphaGenome in more than half a million experiments and it was performing very well.<\/p>\n

But he said it was “far from perfect” and there was still a lot of work to do.<\/p>\n

“It’s a really exciting time with three areas where the UK is world-leading – genomics, biomedical research and AI – combining to transform biology and medicine,” Prof Lehner said.<\/p>\n

The team at DeepMind won the Nobel Prize for Chemistry in 2024 for their work on AlphaFold \u2013 an AI system that predicts the 3D structure of proteins in the body.<\/p>\n

“I think we are at the start of a new era of scientific progress, and AI is going to enable a number of different breakthroughs,” says Pushmeet Kohli, vice president of science and strategic initiatives at Google DeepMind.<\/p>\n","protected":false},"excerpt":{"rendered":"Latysheva said she was “really excited” by the AI model’s potential to understand which mutations cause disease and…\n","protected":false},"author":2,"featured_media":395367,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[554,733,4308,86,56,54,55],"class_list":{"0":"post-395366","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-artificial-intelligence","8":"tag-ai","9":"tag-artificial-intelligence","10":"tag-artificialintelligence","11":"tag-technology","12":"tag-uk","13":"tag-united-kingdom","14":"tag-unitedkingdom"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/395366","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/comments?post=395366"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/395366\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media\/395367"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media?parent=395366"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/categories?post=395366"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/tags?post=395366"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}