On its website, the NHS says serotonin syndrome is usually triggered when you take an SSRI with another medication or substance that also raises serotonin levels, for example another antidepressant or St John\u2019s Wort.<\/a><\/p>\nSymptoms include confusion, agitation, muscle twitching, sweating, shivering and diarrhoea.<\/p>\n
If you experience symptoms of serotonin syndrome, you should seek immediate advice from your GP or specialist. If this isn\u2019t possible, phone 111.<\/p>\n
If you are taking SSRIs and have a very high temperature, seizures, irregular heartbeat, feel disorientated or become unconscious, 999 should be called.<\/p>\n
Patients prescribed antidepressants are advised to consult their doctor about any changes, or before stopping taking medication.<\/p>\n
Singer Lewis Capaldi has been candid about taking sertraline to manage his severe anxiety and panic attacks.<\/p>\n
In July, he told The Sun he was no longer taking the antidepressant and accepted he would always have some level of anxiety.<\/p>\n
During a live stream, Lewis told fans: \u201cIt was f***ing hard to get off it. You could say I\u2019ve survived getting off sertraline but let\u2019s not get into that. This is happy stuff. I\u2019m trying to share less.\u201d<\/p>\n<\/p>\n
![\"Singer](\"data:image\/svg+xml,%3Csvg)
Singer Lewis Capaldi, pictured in July 2025, said therapy had played a \u2018massive part\u2019 in his return to music and has been honest about his use of antidepressants. Picture: Yui Mok\/PA<\/p>\n
At an inquest into the death of retail assistant Grace Uludag at Oakwood House in Maidstone on February 23, assistant coroner Venessa Holt explained toxicology tests were carried out and the results indicated sertraline at a potentially fatal level.<\/p>\n
It was recorded as 1.94 milligrams of sertraline per litre of blood which suggested an overdose.<\/p>\n
The toxicologist noted that a concentration of sertraline above 1.5 milligrams per litre of blood is known to be a contributing factor in death.<\/p>\n
A statement read on behalf of the family explained that there was never any indication their mum was suicidal, and she had never expressed any wish to die.<\/p>\n
\u201cShe lived for her family and grandchildren, who brought her joy and miss her,\u201d it read.<\/p>\n
It explained that the family made sure she took her medication, and everyone knew what was needed on each day by using a dosette box to organise what she took and when.<\/p>\n
The coroner’s court at Oakwood House, Maidstone<\/p>\n
During the inquest, her daughter had questions for the coroner as to how an overdose could have occurred.<\/p>\n
\u201cShe [Grace] wanted to feel better. She did not expect all of this,\u201d she said.<\/p>\n
\u201cMy concern, was it the dose, was it too high? I am very confused on why that happened.\u201d<\/p>\n
The court heard how Grace was feeling dizzy and struggling to breathe the day before her death and had called her GP surgery who advised her to ring 999.<\/p>\n
The family explained Grace was often reluctant to go to A&E due to long waiting times, which put her in significant discomfort.<\/p>\n
The next day, Grace felt dizzy and fell onto the floor and hit her head on a wall, which prompted her daughter to ring for an ambulance.<\/p>\n
\u2018She lived for her family and grandchildren, who brought her joy and miss her\u2019<\/p>\n
Once in the company of paramedics, she suffered a cardiac arrest and died at home.<\/p>\n
In her conclusion, the coroner said: \u201cI am satisfied she died as a result of an overdose but there is no evidence it was intentional.<\/p>\n
\u201cThere was never any indication of her being suicidal.<\/p>\n
\u201cShe contacted the GP the day before because she felt unwell and dizzy.\u201d<\/p>\n
The medical cause of death was recorded as an accidental sertraline overdose which the coroner said was both an \u201cunexpected and unintended consequence\u201d.<\/p>\n
According to the NHS, SSRIs can be used to treat many mental health conditions, such as depression and anxiety, but can sometimes be used to treat other conditions like menopause and irritable bowel syndrome.<\/p>\n
It\u2019s thought that SSRIs work by increasing serotonin levels in the brain.<\/p>\n","protected":false},"excerpt":{"rendered":"A grandmother died after accidentally taking an overdose of a commonly prescribed antidepressant, an inquest heard. Grace Uludag,…\n","protected":false},"author":2,"featured_media":457036,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[59,3862,102,192,12178,191,194,56,54,55],"class_list":["post-457035","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-gb","tag-gravesham","tag-health","tag-human-interest","tag-inquests","tag-kent","tag-syndicate","tag-uk","tag-united-kingdom","tag-unitedkingdom"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/457035","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/comments?post=457035"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/457035\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media\/457036"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media?parent=457035"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/categories?post=457035"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/tags?post=457035"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}