{"id":519042,"date":"2026-04-08T06:45:08","date_gmt":"2026-04-08T06:45:08","guid":{"rendered":"https:\/\/www.newsbeep.com\/uk\/519042\/"},"modified":"2026-04-08T06:45:08","modified_gmt":"2026-04-08T06:45:08","slug":"organ-donors-skin-patch-helped-patient-discover-new-lung-was-being-rejected-uk-news","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/uk\/519042\/","title":{"rendered":"Organ donor&#8217;s skin patch helped patient discover new lung was being rejected | UK News"},"content":{"rendered":"<p>A skin patch from an organ donor helped a patient discover his body was rejecting his new lung, leading him to get swifter treatment.<\/p>\n<p>Darren White was one of the first lung transplant patients to have a patch from their donor grafted onto the skin.<\/p>\n<p>The 53-year-old was given steroids when tests showed his body was rejecting his lung three months after the operation.<\/p>\n<p>Over a year later, he is doing well and said he can now be &#8220;more of a dad&#8221; to his toddler, Daniel, because he can walk and take him to the park.<\/p>\n<p>Experts leading the Sentinel trial said the skin flap, which is grafted on to patients&#8217; forearms at the same time of their lung transplant, acts as a window.<\/p>\n<p>          <img decoding=\"async\" class=\"sdc-article-image__item\" loading=\"lazy\" intrinsicsize=\"768x432\" src=\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2026\/04\/skynews-darren-white-lung-transplant_7213270.jpg\"   alt=\"The 53-year-old and his son Daniel. Pic: PA\" data-testid=\"article-image-image\"\/><\/p>\n<p>        Image:<br \/>\n        The 53-year-old and his son Daniel. Pic: PA<\/p>\n<p>Scientists believe the skin reacts earlier than other organs and is more visible, meaning medics can treat rejection as soon as a rash appears in order to cut the risk of permanent damage.<\/p>\n<p>So far 10 patients have received 10cm by 3cm patches from their organ donor as part of the study.<\/p>\n<p>In 2024, the former bus driver was diagnosed with lung fibrosis, which causes the lungs to become scarred and leads to breathing difficulties.<\/p>\n<p>He had a transplant later that year and said he did not hesitate to agree when approached about the Sentinel trial while he was on the waiting list.<\/p>\n<p>&#8220;Anything that might help to avoid rejection was worth a try,&#8221; Mr White, from Stockton-on-Tees, County Durham, said.<\/p>\n<p>&#8220;Rejection is the biggest fear of any transplant recipient, so having something that might be able to catch it much sooner than otherwise was really appealing.&#8221;<\/p>\n<p>          <img decoding=\"async\" class=\"sdc-article-image__item\" loading=\"lazy\" intrinsicsize=\"768x432\" src=\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2026\/04\/skynews-darren-white-lung-transplant_7213271.jpg\"   alt=\"The skin patch grafted on to Mr White's forearm. Pic: PA\" data-testid=\"article-image-image\"\/><\/p>\n<p>        Image:<br \/>\n        The skin patch grafted on to Mr White&#8217;s forearm. Pic: PA<\/p>\n<p>Lung rejection is typically hard to detect because it can involve blood tests, biopsies and X-rays, according to NHS Blood and Transplant (NHSBT).<\/p>\n<p>Rates of rejection are typically highest in the first three to six months post-surgery and occur in almost a third of patients.<\/p>\n<p>Three months after his transplant, Mr White noticed a purple rash on the flap and sent photos to doctors.<\/p>\n<p>A biopsy showed mild rejection, and he was treated with steroids.<\/p>\n<p>Read more from Sky News:<br \/><a href=\"https:\/\/news.sky.com\/story\/taxi-driver-jailed-for-raping-woman-on-her-way-home-from-night-out-13528873\" target=\"_blank\" rel=\"nofollow noopener\">Taxi driver raped woman on night out<\/a><br \/><a href=\"https:\/\/news.sky.com\/story\/australian-sas-veteran-ben-roberts-smith-charged-with-war-crime-murders-in-afghanistan-13528789\" target=\"_blank\" rel=\"nofollow noopener\">Decorated veteran charged with war crimes<\/a><\/p>\n<p>     <a href=\"https:\/\/news.sky.com\/download-app\" target=\"blank\" data-tracking-label=\"ui-app-promo-download-link\" class=\"ui-app-promo sdc-article-widget\" data-type=\"\" data-component-name=\"ui-app-promo\" data-testid=\"app-promo\" rel=\"nofollow noopener\"><\/p>\n<p>    <\/a><\/p>\n<p>&#8220;I definitely believe the skin patch helped to stop the lungs from being rejected,&#8221; Mr White said.<\/p>\n<p>&#8220;I was feeling fine; there was no reason for me to think that the lungs were being rejected. The only sign was the rash.<\/p>\n<p>&#8220;I&#8217;m over a year post-transplant now and doing really well.&#8221;<\/p>\n<p>The Sentinel trial is set to run until 2027 and will recruit 152 patients. The families of donors must consent for the skin transplant to take place.<\/p>\n<p>Henk Giele, chief investigator of Sentinel and a plastic surgeon in Oxford, said: &#8220;It seems logical that having a window to your transplant can provide an early warning system of rejection or reassure you that you don&#8217;t have rejection, but we have to prove it works.<\/p>\n<p>&#8220;We are so grateful to the patients, the donors and their families, the transplant teams, and the NHSBT staff who make this important trial happen.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"A skin patch from an organ donor helped a patient discover his body was rejecting his new lung,&hellip;\n","protected":false},"author":2,"featured_media":519043,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[59,102,56,54,55],"class_list":{"0":"post-519042","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-gb","9":"tag-health","10":"tag-uk","11":"tag-united-kingdom","12":"tag-unitedkingdom"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/519042","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/comments?post=519042"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/519042\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media\/519043"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media?parent=519042"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/categories?post=519042"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/tags?post=519042"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}