{"id":519275,"date":"2026-04-08T09:45:09","date_gmt":"2026-04-08T09:45:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/uk\/519275\/"},"modified":"2026-04-08T09:45:09","modified_gmt":"2026-04-08T09:45:09","slug":"skin-patch-from-donor-helped-patient-spot-transplant-rejection","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/uk\/519275\/","title":{"rendered":"Skin patch from donor helped patient spot transplant rejection"},"content":{"rendered":"<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">According to NHS Blood and Transplant, lung rejection is hard to detect as it can involve blood tests, biopsies and x-rays &#8211; despite happening in almost a third of patients.<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">Three months after having his transplant, White noticed a purple rash on the skin patch &#8211; with a biopsy showing mild rejection before he was treated with steroids.<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">&#8220;I definitely believe the skin patch helped to stop the lungs from being rejected,&#8221; he said.<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">&#8220;I&#8217;m over a year post-transplant now and doing really well. Who knows if that would be the case if the rash hadn&#8217;t shown up and rejection wasn&#8217;t spotted until further down the line.&#8221;<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">The Sentinel trial skin grafts are being carried out by plastic surgeons at the University of Oxford.<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">Henk Giele, chief investigator of Sentinel and an Oxford plastic surgeon said: &#8220;It seems logical that having a window to your transplant can provide an early warning system of rejection or reassure you that you don&#8217;t have rejection but we have to prove it works.<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">&#8220;We hope it will change what we know about transplant and makes patients lives better and longer,&#8221; he added.<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">The trial is set to run until 2027 and will recruit 152 patients at five centres; Freeman Hospital in Newcastle, Harefield Hospital in London, Queen Elizabeth Hospital in Birmingham, Royal Papworth in Cambridge and Wythenshawe Hospital in Greater Manchester.<\/p>\n","protected":false},"excerpt":{"rendered":"According to NHS Blood and Transplant, lung rejection is hard to detect as it can involve blood tests,&hellip;\n","protected":false},"author":2,"featured_media":519276,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[59,102,56,54,55],"class_list":{"0":"post-519275","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-gb","9":"tag-health","10":"tag-uk","11":"tag-united-kingdom","12":"tag-unitedkingdom"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/519275","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/comments?post=519275"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/519275\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media\/519276"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media?parent=519275"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/categories?post=519275"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/tags?post=519275"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}