![\"Christina](\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2026\/04\/SEI_288018583-ef0d.jpg\")
\n\t\tChristina Applegate talks openly about the mental and physical toll the MS takes on her (Picture: Gilbert Flores\/Variety via Getty Images)<\/p>\n
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\n\t\tChristina Applegate talks openly about the mental and physical toll the MS takes on her (Picture: Gilbert Flores\/Variety via Getty Images)<\/p>\n
Christina Applegate<\/a> was diagnosed with\u00a0multiple sclerosis<\/a>\u00a0in\u00a02021, and friends say they are\u00a0aware she \u2018might not have a tomorrow\u2019.\u00a0\u00a0<\/p>\n The Anchorman star\u00a0is thought to have been hospitalised in late\u00a0March\u00a0but\u00a0the\u00a0reason why\u00a0is\u00a0unclear.\u00a0<\/p>\n Applegate, 54, has been living with the condition for five years, and\u00a0friends are worried about her.\u00a0\u00a0<\/p>\n Earlier this year, she said she was mostly bed bound and revealed her favourite thing to do was take her\u00a015-year-old\u00a0daughter to school. \u00a0\u00a0<\/p>\n Speaking to\u00a0People magazine<\/a>\u00a0at the time, she said: \u2018I tell myself, \u201cJust get her there safely and get home so you can get back into bed.\u201d And\u00a0that\u2019s\u00a0what I do.\u2019\u00a0\u00a0<\/p>\n \t\t\t\tGet personalised updates on all things Netflix\t\t\t<\/p>\n Wake up to find news on your TV shows in your inbox every morning with Metro\u2019s TV Newsletter.<\/p>\n Sign up to our newsletter<\/a> and then select your show in the link we\u2019ll send you so we can get TV news tailored to you.<\/p>\n After TMZ<\/a> claimed the star is in hospital,\u00a0a source close to Christina\u2019s situation told the\u00a0Daily Mail<\/a>: \u2018With every setback, if we are being realistic, everyone has it in the back of their minds that they might not have a tomorrow with her.\u2019\u00a0<\/p>\n \t\t They said that Christina was in \u2018rough shape\u2019 but that \u2018people aren\u2019t thinking this is the end\u2019.\u00a0\u00a0<\/p>\n The source continued: \u2018Nobody is planning to be at a funeral.\u00a0Granted, her disease will take her sooner than anyone would like it to be, but everyone has trust in her medical team and her will to live.\u2019\u00a0<\/p>\n In\u00a0June\u00a02024,\u00a0Applegate, who played Rachel\u2019s sister in\u00a0Friends,\u00a0told Jamie-Lynn Sigler on her podcast<\/a>\u00a0MeSsy<\/a>\u00a0that she \u2018doesn\u2019t enjoy living\u2019<\/a>.\u00a0<\/p>\n Months\u00a0before, she revealed on Dax Shepard\u2019s Armchair Expert podcast<\/a> that she had 30 lesions on her brain<\/a>: \u2018My biggest one is behind my right eye, so my right eye hurts a lot.\u2019\u00a0\u00a0<\/p>\n She has talked\u00a0frequently and openly\u00a0about her frustrations and struggles with MS, which caused her to step\u00a0out of the\u00a0spotlight.\u00a0<\/p>\n Applegate was\u00a0mid-production for\u00a0the third and final season of hit Netflix<\/a> show Dead to Me when\u00a0she was diagnosed\u00a0with the condition.\u00a0<\/p>\n \t\t \t\t Later she revealed that she remembers experiences the \u2018first signs of MS\u2019 while filming the pilot.\u00a0\u00a0<\/p>\n In a conversation with executive producer Liz Feldman on her podcast,\u00a0Applegate said: \u2018Not to bring everyone down but there it was.\u2019\u00a0<\/p>\n Feldman remarked: \u2018I remember you losing your balance when we were shooting the pilot a couple of times.\u2019\u00a0\u00a0<\/p>\n In March, Applegate released a memoir, You\u00a0With\u00a0The\u00a0Sad Eyes,\u00a0detailing her life as a child star, but also the abuse and turbulence she went through to\u00a0get where she is today.\u00a0\u00a0<\/p>\n A representative for Applegate told the Daily Mail:\u00a0\u2018I have no comment on whether she is in the hospital or what her medical treatments are.\u00a0<\/p>\n \u2018She\u2019s had a long history of complicated medical conditions that she has been refreshingly open about, as evidenced in her memoir and on her podcast.\u2019\u00a0<\/p>\n Metro has reached out to Applegate\u2019s representative for comment. \u00a0\u00a0<\/p>\n Got a story?<\/p>\n If you\u2019ve got a celebrity story, video or pictures get in touch with the Metro.co.uk<\/a> entertainment team by emailing us celebtips@metro.co.uk, calling 020 3615 2145 or by visiting our Submit Stuff<\/a> page \u2013 we\u2019d love to hear from you.<\/p>\n Arrow Arrow Arrow![\"LOS](\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2026\/04\/SEI_288018511-f6e6-e1776516551465.jpg\")
\n\t\tThe actor\u2019s bio on Instagram reads: Mom, Actor, Dancer, Lady with a cool cane,\u00a0@messypodcast\u00a0Author of You With the Sad Eyes (Picture: Monica Schipper\/WireImage)<\/p>\n![\"Brad](\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2026\/04\/SEI_287748455-5b20.jpg\")
\n\t\tApplegate went with Brad Pitt as her date to the MTV Video Music Awards (Picture: Jeff Kravitz\/FilmMagic)<\/p>\n![\"Christina](\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2026\/04\/SEI_293474275-2590-e1776517318351.jpg\")
\n\t\tApplegate consolidated her acting career on the Fox show Married\u2026 With Children (Picture: BauerGriffin\/Instarimages\/Cover Images)<\/p>\n
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