{"id":598872,"date":"2026-05-22T23:53:08","date_gmt":"2026-05-22T23:53:08","guid":{"rendered":"https:\/\/www.newsbeep.com\/uk\/598872\/"},"modified":"2026-05-22T23:53:08","modified_gmt":"2026-05-22T23:53:08","slug":"ai-used-to-speed-up-search-for-motor-neurone-disease-drugs","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/uk\/598872\/","title":{"rendered":"AI used to speed up search for motor neurone disease drugs"},"content":{"rendered":"<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">Because the drugs have already been developed and approved, redeploying them can be more straightforward than starting from scratch with new formulas.<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">Discovering new drugs and getting them to market can take a long time &#8211; more than 10 years, according to some estimates.<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">But Prof Chandran and his team believe their work means affordable, effective drugs for neurological conditions could come much sooner.<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">The research is not the first to explore how AI can surface potential solutions hidden in mountains of health or medical data.<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">Scientists at the Massachusetts Institute of Technology in Cambridge, US, have used generative AI to identify novel antibiotic compounds that <a href=\"https:\/\/www.bbc.co.uk\/news\/articles\/cgr94xxye2lo\" class=\"ssrcss-1e0jzsh-InlineLink e1kn3p7n0\" rel=\"nofollow noopener\" target=\"_blank\">might be able to treat superbugs including gonorrhoea and conditions such as Parkinson&#8217;s<\/a>.<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">And in 2024 researchers at Harvard University <a href=\"https:\/\/hms.harvard.edu\/news\/researchers-harness-ai-repurpose-existing-drugs-treatment-rare-diseases\" class=\"ssrcss-1e0jzsh-InlineLink e1kn3p7n0\" rel=\"nofollow noopener\" target=\"_blank\">developed a neural network model called TxGNN, external<\/a> to surface existing drugs which could be used to treat rare conditions.<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">But there have been setbacks in the wider field of research.<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">A recent review of lecanemab and donanemab, once hailed as &#8220;breakthrough&#8221; drugs to treat Alzheimer&#8217;s, found despite slowing its progression it was not significant enough to make a meaningful difference to patients.<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">It looked at 17 studies, involving 20,342 volunteers, of drugs that remove amyloid &#8211; a misfolded protein present in disease &#8211; from the brain. <\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">Its conclusion <a href=\"https:\/\/www.bbc.co.uk\/news\/articles\/cql77wlqlx7o\" class=\"ssrcss-1e0jzsh-InlineLink e1kn3p7n0\" rel=\"nofollow noopener\" target=\"_blank\">sparked a backlash from other scientists<\/a>.<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">But Professor Chandran remains confident &#8220;we&#8217;re at the tipping point of change&#8221; in neurological research and understanding.<\/p>\n","protected":false},"excerpt":{"rendered":"Because the drugs have already been developed and approved, redeploying them can be more straightforward than starting from&hellip;\n","protected":false},"author":2,"featured_media":598873,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[554,733,4308,86,56,54,55],"class_list":["post-598872","post","type-post","status-publish","format-standard","has-post-thumbnail","category-artificial-intelligence","tag-ai","tag-artificial-intelligence","tag-artificialintelligence","tag-technology","tag-uk","tag-united-kingdom","tag-unitedkingdom"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/598872","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/comments?post=598872"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/598872\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media\/598873"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media?parent=598872"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/categories?post=598872"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/tags?post=598872"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}