{"id":640286,"date":"2026-06-15T18:26:09","date_gmt":"2026-06-15T18:26:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/uk\/640286\/"},"modified":"2026-06-15T18:26:09","modified_gmt":"2026-06-15T18:26:09","slug":"the-link-between-vitamin-c-and-brain-health-just-got-even-clearer-sciencealert","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/uk\/640286\/","title":{"rendered":"The Link Between Vitamin C And Brain Health Just Got Even Clearer : ScienceAlert"},"content":{"rendered":"<p>We can&#8217;t make our own  <a href=\"https:\/\/www.sciencealert.com\/what-are-vitamins-and-do-we-really-need-to-take-them\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73116\" data-postid=\"204919\" rel=\"nofollow noopener\" target=\"_self\">vitamin<\/a> C, so we need to imbibe enough of this essential nutrient <a href=\"https:\/\/www.sciencealert.com\/you-should-eat-more-of-these-8-healthy-foods-and-heres-why\" rel=\"nofollow noopener\" target=\"_blank\">through our diets<\/a>.<\/p>\n<p>Through our bodies it flows, from the stomach, into the blood, and up to the brain.<\/p>\n<p>Past studies have hinted at how important vitamin C is to brain function. It concentrates in <a href=\"https:\/\/doi.org\/10.1016\/j.freeradbiomed.2008.12.018\" rel=\"nofollow noopener\" target=\"_blank\">brain tissue<\/a>, with the cerebrospinal fluid that bathes the brain containing <a href=\"https:\/\/doi.org\/10.1016\/j.freeradbiomed.2008.12.018\" rel=\"nofollow noopener\" target=\"_blank\">twice as much<\/a> vitamin C as blood.<\/p>\n<p>A decent vitamin C intake <a href=\"https:\/\/doi.org\/10.1001\/jama.287.24.3223\" rel=\"nofollow noopener\" target=\"_blank\">has also been linked<\/a> to a lower risk of developing  <a href=\"https:\/\/www.sciencealert.com\/go\/IaO\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73015\" data-postid=\"204919\" rel=\"nofollow noopener\" target=\"_self\">Alzheimer&#8217;s<\/a> disease.<\/p>\n<p>Now, new research tells us something more about how vitamin C may lead to better brain health in later years.<\/p>\n<p>We know that vitamin C is an antioxidant and is involved in a flurry of chemical reactions in our bodies. But we don&#8217;t know much about how levels of vitamin C in the blood (which is more easily sampled) might relate to brain health.<\/p>\n<p>To get some more clarity, researchers at Hirosaki University in Japan took blood samples from 2,044 volunteers with a median age of 69, and studied how levels of vitamin C in those samples matched up to certain features on <a href=\"https:\/\/en.wikipedia.org\/wiki\/Functional_magnetic_resonance_imaging\" rel=\"nofollow noopener\" target=\"_blank\">brain scans<\/a>.<\/p>\n<p>They were particularly interested in a key brain circuit called the <a href=\"https:\/\/neuroscientificallychallenged.com\/posts\/know-your-brain-default-mode-network\" rel=\"nofollow noopener\" target=\"_blank\">default mode network<\/a> (DMN) that ticks away quietly, connecting many parts of the brain, even when you think you&#8217;re doing nothing.<\/p>\n<p>A loosening of the DMN has also been linked to cognitive decline, so the researchers wanted to see how tight those connections were among elderly Japanese people.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2026\/06\/1781547968_405_0.jpg\" alt=\"YouTube Thumbnail\" tabindex=\"0\" role=\"button\" class=\"youtube-thumbnail-preview\" loading=\"lazy\"\/> frameborder=&#8221;0\u2033 allow=&#8221;accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share&#8221; referrerpolicy=&#8221;strict-origin-when-cross-origin&#8221; allowfullscreen&gt;<\/p>\n<p>There was a clear relationship across the participants in the study: More vitamin C in the blood was associated with a higher volume of gray matter, the brain tissue that handles memory, movement and emotion.<\/p>\n<p>Higher vitamin C levels also correlated with stronger connectivity in the DMN.<\/p>\n<p>This was just a one-time assessment though, so it doesn&#8217;t prove that vitamin C directly affected those brain connections. Rather, it suggests that vitamin C may have a role in keeping brains healthy \u2013 and maybe, at a stretch, help <a href=\"https:\/\/www.sciencealert.com\/the-roots-of-dementia-trace-back-all-the-way-to-childhood-experts-reveal\" rel=\"nofollow noopener\" target=\"_blank\">ward off dementia<\/a>.<\/p>\n<p>&#8220;This finding generates the exciting hypothesis that a diet rich in vitamin C might play a supportive role in maintaining brain health and mitigating age-related cognitive decline in older adults,&#8221; <a href=\"https:\/\/www.eurekalert.org\/news-releases\/1130672\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> radiologist Tomohiro Shintaku, from Hirosaki University.<\/p>\n<p>The DMN links several important brain regions, including the <a href=\"https:\/\/en.wikipedia.org\/wiki\/Ventromedial_prefrontal_cortex\" rel=\"nofollow noopener\" target=\"_blank\">ventromedial prefrontal cortex<\/a> near the front of our brain (linked to processing risk, fear, and emotions), and the <a href=\"https:\/\/en.wikipedia.org\/wiki\/Posterior_cingulate_cortex\" rel=\"nofollow noopener\" target=\"_blank\">posterior cingulate cortex<\/a> at the center (involved with memory and <a href=\"https:\/\/www.sciencealert.com\/the-neuroscience-of-why-some-athletes-keep-getting-better-as-they-age\" rel=\"nofollow noopener\" target=\"_blank\">motor control<\/a>).<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2026\/06\/DefaultModeNetwork.jpg\" alt=\"Default Mode Network\" width=\"642\" height=\"386\" class=\"wp-image-204924 size-full\"   loading=\"lazy\"\/>The default mode network links several crucial processing regions of the brain. (Menon, <a href=\"https:\/\/doi.org\/10.1016\/j.neuron.2023.04.023\" rel=\"nofollow noopener\" target=\"_blank\">Neuron<\/a>, 2023)<\/p>\n<p>As a whole, the DMN has been associated with a <a href=\"https:\/\/doi.org\/10.1016\/j.neuron.2023.04.023\" rel=\"nofollow noopener\" target=\"_blank\">host of different cognitive functions<\/a>, covering what we remember about ourselves and how we refer to ourselves, thinking about the future, and <a href=\"https:\/\/doi.org\/10.1016\/j.neuroimage.2017.01.044\" rel=\"nofollow noopener\" target=\"_blank\">controlling our attention<\/a>.<\/p>\n<p>Past studies have found that people with <a href=\"https:\/\/doi.org\/10.1148\/radiol.10091701\" rel=\"nofollow noopener\" target=\"_blank\">Alzheimer&#8217;s disease<\/a>, <a href=\"https:\/\/doi.org\/10.1212\/WNL.0b013e31827689d6\" rel=\"nofollow noopener\" target=\"_blank\">Parkinson&#8217;s disease<\/a>, and <a href=\"https:\/\/doi.org\/10.1007\/s11065-012-9199-9\" rel=\"nofollow noopener\" target=\"_blank\">depression<\/a> tend to have weaker, less well-connected DMN.<\/p>\n<p>There&#8217;s a lot more research required to look into these relationships in more detail, but the implication is that a healthy amount of vitamin C could help keep the DMN running more smoothly, and ward off some of these <a href=\"https:\/\/www.sciencealert.com\/scientists-found-2-existing-drugs-could-reverse-alzheimers-brain-damage-in-mice\" rel=\"nofollow noopener\" target=\"_blank\">brain health disorders<\/a>.<\/p>\n<p>&#8220;To the best of our knowledge, this is the first study to demonstrate the association between plasma vitamin C levels and DMN connectivity,&#8221; <a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0348504\" rel=\"nofollow noopener\" target=\"_blank\">write<\/a> the researchers in their published paper.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2026\/06\/BrainScans.jpg\" alt=\"Brain connectivity\" width=\"642\" height=\"1092\" class=\"wp-image-204922 size-full\"   loading=\"lazy\"\/>The researchers looked at three regions of gray matter that make up the default mode network, and related this to levels of vitamin C in blood samples. (Nagaya et al., PLOS One, 2026)<\/p>\n<p>In their analysis, the researchers adjusted for several factors that may also impact brain health, including age, sex, and health conditions such as <a href=\"https:\/\/www.sciencealert.com\/scientists-may-have-found-a-new-cause-of-high-blood-pressure-and-a-way-to-treat-it\" rel=\"nofollow noopener\" target=\"_blank\">high blood pressure<\/a>.<\/p>\n<p>But they want to see whether they can replicate their findings in longitudinal studies that track people over several years, and in more diverse groups. That will help us understand if the associations found here, in relatively elderly people living in Japan, apply to other populations or age groups.<\/p>\n<p>Even so, it&#8217;s another reason to think about getting more vitamin C into your diet. It&#8217;s found not just in oranges, the best-known source, but in many other <a href=\"https:\/\/www.sciencealert.com\/9-foods-that-pack-more-vitamin-c-than-an-orange\" rel=\"nofollow noopener\" target=\"_blank\">fruits and vegetables<\/a>.<\/p>\n<p><a href=\"https:\/\/www.sciencealert.com\/newsletter?utm_source=promo_stargazing\" rel=\"nofollow noopener\" target=\"_blank\"><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2026\/05\/FOMO-1200x628-_Dont-miss-the-next-breakthrough_-cosmic-colourful-642x336.jpg\" alt=\"Subscribe to ScienceAlert's free fact-checked newsletter\" width=\"642\" height=\"336\" class=\"alignnone wp-image-201722 size-medium\"   loading=\"lazy\"\/><\/a><\/p>\n<p>Previous studies have linked optimal levels of vitamin C to a <a href=\"https:\/\/www.sciencealert.com\/does-vitamin-c-really-protect-you-from-the-common-cold\" rel=\"nofollow noopener\" target=\"_blank\">stronger immune system<\/a> \u2013 but it doesn&#8217;t do much <a href=\"https:\/\/www.sciencealert.com\/does-vitamin-c-really-protect-you-from-the-common-cold\" rel=\"nofollow noopener\" target=\"_blank\">for the common cold<\/a>.<\/p>\n<p>Suggestions that it may also protect <a href=\"https:\/\/www.sciencealert.com\/a-common-vitamin-could-help-protect-your-lungs-from-air-pollution\" rel=\"nofollow noopener\" target=\"_blank\">against air pollution<\/a>, be the secret to <a href=\"https:\/\/www.sciencealert.com\/common-vitamin-could-be-the-secret-to-younger-looking-skin\" rel=\"nofollow noopener\" target=\"_blank\">younger-looking skin<\/a> \u2013 or boost brain health \u2013 may not be so clear-cut.<\/p>\n<p>These associations are certainly worth exploring, and in the meantime, are a reminder of the benefits of eating a well-rounded diet while scientists dig into the details.<\/p>\n<p>Related: <a href=\"https:\/\/www.sciencealert.com\/a-small-part-of-your-brain-may-still-be-listening-under-anesthesia\" rel=\"nofollow noopener\" target=\"_blank\">A Small Part of Your Brain May Still Be Listening Under Anesthesia<\/a><\/p>\n<p>&#8220;What I found most fascinating about this research is that we were able to detect these subtle but significant associations between a single nutritional factor and large-scale brain networks by utilizing a robust, community-based cohort of over 2,000 older adults,&#8221; <a href=\"https:\/\/www.eurekalert.org\/news-releases\/1130672\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> Shintaku.<\/p>\n<p>&#8220;It truly highlights the potential impact of our everyday dietary habits on our brain structures.&#8221;<\/p>\n<p>The research has been published in <a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0348504\" rel=\"nofollow noopener\" target=\"_blank\">PLOS One<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"We can&#8217;t make our own vitamin C, so we need to imbibe enough of this essential nutrient through&hellip;\n","protected":false},"author":2,"featured_media":640287,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[45],"tags":[102,249,6636,56,54,55],"class_list":["post-640286","post","type-post","status-publish","format-standard","has-post-thumbnail","category-nutrition","tag-health","tag-msft-content","tag-nutrition","tag-uk","tag-united-kingdom","tag-unitedkingdom"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/640286","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/comments?post=640286"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/640286\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media\/640287"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media?parent=640286"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/categories?post=640286"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/tags?post=640286"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}