{"id":654621,"date":"2026-06-23T20:45:09","date_gmt":"2026-06-23T20:45:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/uk\/654621\/"},"modified":"2026-06-23T20:45:09","modified_gmt":"2026-06-23T20:45:09","slug":"joe-manganiello-reveals-life-threatening-health-battle-resulting-in-amputation","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/uk\/654621\/","title":{"rendered":"Joe Manganiello reveals life-threatening health battle resulting in &#8216;amputation&#8217;"},"content":{"rendered":"<p>Joe Manganiello revealed he suffered from life-threatening autoimmune-related illnesses that resulted in him having an amputation.<\/p>\n<p>In the synopsis of the \u201cSpider-Man\u201d actor\u2019s forthcoming memoir, <a href=\"https:\/\/www.simonandschuster.com\/books\/Bloodlines\/Joe-Manganiello\/9781668207109\" target=\"_blank\" rel=\"nofollow noopener\" data-nyp-affiliate=\"true\">\u201cBloodlines,\u201d<\/a> he said he dealt with \u201ca cascade of autoimmune-related illnesses\u201d that attacked his thyroid, digestive system, skin, lungs and eyes.<\/p>\n<p>During the seven-year battle, Manganiello, 49, dealt with \u201cchronic pain, a life-saving organ amputation, existential crisis and a prolonged fight for survival that left doctors with few answers and no clear explanation.\u201d<\/p>\n<p id=\"mntl-sc-block_10-0\">When doctors were unable to explain what was happening to the \u201cMagic Mike\u201d star, he turned to an unorthodox form of treatment. <\/p>\n<p>Joe Manganiello (seen above with his dog) suffered from life-threatening autoimmune-related illnesses. Instagram\/joemanganiello<\/p>\n<p>In his forthcoming memoir, \u201cBloodlines,\u201d the \u201cSpider-Man\u201d star said the illness attacked his thyroid, digestive system, skin, lungs and eyes. Simon &amp; Schuster<\/p>\n<p id=\"mntl-sc-block_10-0\">Manganiello used \u201cshamans, pagan rituals, ancient myths, long-lost family records and the rebirth of his own spirituality\u201d to try to aid his illness. <\/p>\n<p id=\"mntl-sc-block_10-0\">The actor also did a deep dive into his own family genealogy and discovered ancestors who survived the Armenian genocide and others who lived with chronic illness.<\/p>\n<p>\u201cIt was the most brutally difficult time of my life, one I wouldn\u2019t wish on my worst enemy, but also my greatest adventure,\u201d Manganiello <a href=\"https:\/\/people.com\/joe-manganiello-announces-tell-all-memoir-bloodlines-exclusive-12004441\" target=\"_blank\" rel=\"noopener nofollow\">told People<\/a> in a statement.<\/p>\n<p>Manganiello (seen above with his dog) dealt with the health issues for seven years. Instagram\/joemanganiello<\/p>\n<p>He had to get \u201ca life-saving organ amputation.\u201d (Pictured: a shirtless Manganiello.) Instagram\/joemanganiello<\/p>\n<p>\u201cI hope that what I went through on this journey can give readers hope that answers and healing may lie for them on the other side of whatever they are fighting through,\u201d he added.<\/p>\n<p>\u201cThe process of writing this book gave me the gift of perspective that helped me to see that my suffering was a cocoon from which I would emerge forever changed.\u201d<\/p>\n<p>It\u2019s unclear when the \u201cTrue Blood\u201d alum dealt with the illness.<\/p>\n<p>\t\t\t\t\t\t\tWant more celebrity and pop culture news?\t\t\t\t\t\t<\/p>\n<p class=\"inline-module__cta\">\n\t\t\t\t\t\t\tStart your day with Page Six Daily.\t\t\t\t\t\t<\/p>\n<p>\t\t\t\t\t\tThanks for signing up!\n\t\t\t\t<\/p>\n<p>Manganiello was married to Sof\u00eda Vergara (seen above with the actor) from 2015 to 2024.  Instagram\/sofiavergara<\/p>\n<p>The \u201cTrue Blood\u201d actor is now engaged to Caitlin\u00a0O\u2019Connor (seen above). Instagram\/caitlin_oconnor<\/p>\n<p>Manganiello was <a href=\"https:\/\/pagesix.com\/article\/sofia-vergara-joe-manganiello-relationship-timeline\/\" rel=\"nofollow noopener\" target=\"_blank\">married to Sof\u00eda Vergara from 2015 to 2024<\/a>. The actor and the \u201cGriselda\u201d star, 53, split because she <a href=\"https:\/\/pagesix.com\/2024\/01\/22\/entertainment\/sofia-vergara-didnt-want-to-be-an-old-mom-in-joe-manganiello-marriage\/\" rel=\"nofollow noopener\" target=\"_blank\">did not want to have any more kids<\/a>.<\/p>\n<p>Manganiello <a href=\"https:\/\/pagesix.com\/2025\/10\/17\/celebrity-news\/joe-manganiello-engaged-to-caitlin-oconnor-after-two-years-of-dating\/\" rel=\"nofollow noopener\" target=\"_blank\">popped the question<\/a> to Catlin O\u2019Connor in June 2025.<\/p>\n<p>\u201cBloodlines\u201d is set to be released on Oct. 13.<\/p>\n","protected":false},"excerpt":{"rendered":"Joe Manganiello revealed he suffered from life-threatening autoimmune-related illnesses that resulted in him having an amputation. In the&hellip;\n","protected":false},"author":2,"featured_media":654622,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[32],"tags":[28267,146964,6491,15665,9401,2755,96,92276,4440,2839,391,56,54,55],"class_list":["post-654621","post","type-post","status-publish","format-standard","has-post-thumbnail","category-celebrities","tag-actors","tag-amputation","tag-celebrities","tag-celebrity-illnesses","tag-celebrity-memoirs","tag-celebrity-news","tag-entertainment","tag-joe-manganiello","tag-mens-health","tag-movies","tag-tv","tag-uk","tag-united-kingdom","tag-unitedkingdom"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/654621","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/comments?post=654621"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/654621\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media\/654622"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media?parent=654621"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/categories?post=654621"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/tags?post=654621"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}