{"id":751953,"date":"2026-08-28T00:42:11","date_gmt":"2026-08-28T00:42:11","guid":{"rendered":"https:\/\/www.newsbeep.com\/uk\/751953\/"},"modified":"2026-08-28T00:42:11","modified_gmt":"2026-08-28T00:42:11","slug":"the-middle-aged-disease-that-makes-you-feel-tired-and-often-goes-undiagnosed","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/uk\/751953\/","title":{"rendered":"The middle-aged disease that makes you feel tired and often goes undiagnosed"},"content":{"rendered":"<p>Your support helps us to tell the story<\/p>\n<p class=\"sc-1uza6dc-0 iOIawn\">From reproductive rights to climate change to Big Tech, The Independent is on the ground when the story is developing. Whether it&#8217;s investigating the financials of Elon Musk&#8217;s pro-Trump PAC or producing our latest documentary, &#8216;The A Word&#8217;, which shines a light on the American women fighting for reproductive rights, we know how important it is to parse out the facts from the messaging.<\/p>\n<p class=\"sc-1uza6dc-0 iOIawn\">At such a critical moment in US history, we need reporters on the ground. Your donation allows us to keep sending journalists to speak to both sides of the story.<\/p>\n<p class=\"sc-1uza6dc-0 iOIawn\">The Independent is trusted by Americans across the entire political spectrum. And unlike many other quality news outlets, we choose not to lock Americans out of our reporting and analysis with paywalls. We believe quality journalism should be available to everyone, paid for by those who can afford it.<\/p>\n<p>Your support makes all the difference.Read more<\/p>\n<p>Diagnoses of a liver condition linked to <a href=\"https:\/\/www.independent.co.uk\/topic\/obesity\" rel=\"nofollow noopener\" target=\"_blank\">obesity<\/a> and <a href=\"https:\/\/www.independent.co.uk\/topic\/type-2-diabetes\" rel=\"nofollow noopener\" target=\"_blank\">type 2 diabetes<\/a> have increased fivefold over a decade, according to a new study.<\/p>\n<p>Researchers noted that despite &#8220;growing recognition&#8221; of metabolic dysfunction-associated steatotic <a href=\"https:\/\/www.independent.co.uk\/topic\/liver-disease\" rel=\"nofollow noopener\" target=\"_blank\">liver disease<\/a> (MASLD) \u2013 previously called non-alcoholic fatty liver disease \u2013 a &#8220;diagnostic gap persists&#8221;.<\/p>\n<p>Triggered by fat building up in the liver, <a href=\"https:\/\/www.independent.co.uk\/topic\/symptoms\" rel=\"nofollow noopener\" target=\"_blank\">symptoms<\/a> include abdominal pain, severe tiredness, and feeling generally unwell.<\/p>\n<p>Overweight or inactive individuals face higher risk, alongside people with type 2 diabetics, the over-50s and those with high blood pressure.<\/p>\n<p>The study by researchers at Queen Mary University of London and the University of Glasgow looked at GP records from almost 12 million people in the UK between 2003 and 2022.<\/p>\n<p>It found that recorded diagnoses of MASLD were 0.02 per cent of adults in 2003, the equivalent of 1,300 people.<\/p>\n<p>This rose to 0.5 per cent in 2012 and 2.4 per cent in 2022, or 283,762 people.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2026\/08\/iStock-1314797892.jpeg\"  loading=\"lazy\" alt=\"It is estimated that almost six million people in the UK are living with diabetes, almost 1.3 million of which may be living with undiagnosed type 2 diabetes\" class=\"sc-1mc30lb-0 ggpMaE\"\/>It is estimated that almost six million people in the UK are living with diabetes, almost 1.3 million of which may be living with undiagnosed type 2 diabetes (Getty\/iStock)<\/p>\n<p>New diagnoses doubled from 2012 to 2022, and those diagnosed with the condition were three times as likely to have type 2 diabetes.<\/p>\n<p>Researchers suggest that a blood test that enables doctors to estimate liver scarring \u201cpresents an opportunity to detect advanced fibrosis\u201d.<\/p>\n<p>People of south Asian ethnicity were also \u201coverrepresented\u201d when it came to MASLD diagnoses.<\/p>\n<p>However, they were least likely to have a score used to estimate liver scarring despite higher levels of type 2 diabetes.<\/p>\n<p>Researchers said \u201cmore progress is needed to reach public health goals in this disease\u201d.<\/p>\n<p>\u201cEqually urgent is the need for additional research to identify and mitigate any risks of compounding health disparities among different ethnic groups especially in the era of medicines with specific indications in this space,\u201d they added.<\/p>\n<p>Based on estimated cases of MASLD cases in Europe, the study found that a \u201csubstantial diagnostic gap remains\u201d in the UK.<\/p>\n<p>Researchers said: \u201cThe current data demonstrate that while UK prevalence has risen substantially to 2.42 per cent, the diagnostic gap remains large compared to expected rates.\u201d<\/p>\n<p>They suggest that, to close the gap, \u201cat-risk groups such as those living with type 2 diabetes and obesity should be identified and case-finding actively pursued\u201d.<\/p>\n<p>It is estimated that almost six million people in the UK are living with diabetes, almost 1.3 million of which may be living with undiagnosed type 2 diabetes.<\/p>\n<p>The latest NHS data also shows that in 2024, 30 per cent of adults aged 16 and over were obese.<\/p>\n","protected":false},"excerpt":{"rendered":"Your support helps us to tell the story From reproductive rights to climate change to Big Tech, The&hellip;\n","protected":false},"author":2,"featured_media":751954,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[59,102,56,54,55],"class_list":["post-751953","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-gb","tag-health","tag-uk","tag-united-kingdom","tag-unitedkingdom"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/751953","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/comments?post=751953"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/751953\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media\/751954"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media?parent=751953"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/categories?post=751953"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/tags?post=751953"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}