{"id":762226,"date":"2026-09-06T20:58:11","date_gmt":"2026-09-06T20:58:11","guid":{"rendered":"https:\/\/www.newsbeep.com\/uk\/762226\/"},"modified":"2026-09-06T20:58:11","modified_gmt":"2026-09-06T20:58:11","slug":"alzheimers-drug-to-be-offered-to-people-without-symptoms-to-stop-it-developing","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/uk\/762226\/","title":{"rendered":"Alzheimer\u2019s drug to be offered to people without symptoms to stop it developing"},"content":{"rendered":"<p>A groundbreaking trial will see healthy adults across Britain with no signs of memory loss given an Alzheimer&#8217;s drug in an attempt to prevent the condition developing<img decoding=\"async\" alt=\"Patients across the UK will be recruited for the study (file photo)\" loading=\"eager\"  src=\"https:\/\/www.newsbeep.com\/uk\/wp-content\/uploads\/2026\/09\/0_Alzheimers-and-dementia-research-conceptual-image.jpg\" \/><\/p>\n<p aria-label=\"Patients across the UK will be recruited for the study (file photo)\" class=\"ImageCaption_caption-title__ccyQU\" data-testid=\"caption-title\">Patients across the UK will be recruited for the study (file photo)(Image: Getty Images\/Science Photo Library RF)<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh\" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">An Alzheimer\u2019s drug is set to be offered to people without symptoms in a bid to stop the disease in its tracks.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh\" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">Participants from across the UK will be given trontinemab as part of a groundbreaking trial which will test how effective the drug is at preventing the onset of the disease.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh\" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">Those taking part in the trial, <a aria-label=\"healthy Link opens in a new tab.\" class=\"TextLink_text-link__dBSS0 TextLink_enabled__dJF3l\" href=\"https:\/\/www.mirror.co.uk\/news\/health\" rel=\"follow nofollow noopener\" tabindex=\"0\" target=\"_blank\">healthy <\/a>adults with no history of memory problems, will be selected after being given <a aria-label=\"blood testsLink opens in a new tab.\" class=\"TextLink_text-link__dBSS0 TextLink_enabled__dJF3l\" href=\"https:\/\/www.mirror.co.uk\/news\/health\/alzheimers-linked-10-health-conditions-36691951\" rel=\"follow nofollow noopener\" tabindex=\"0\" target=\"_blank\">blood tests<\/a> for levels of protein taul, which can indicate biological signs of <a aria-label=\"Alzheimer&#039;s Link opens in a new tab.\" class=\"TextLink_text-link__dBSS0 TextLink_enabled__dJF3l\" href=\"https:\/\/www.mirror.co.uk\/news\/health\/early-dementia-alzheimers-symptoms-changes-37235677\" rel=\"follow nofollow noopener\" tabindex=\"0\" target=\"_blank\">Alzheimer&#8217;s <\/a>years before symptoms emerge.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh\" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">They will then be given the drug in three monthly transfusions, with research suggesting that this can help clear buildups of plaque known to trigger the form of <a aria-label=\"dementiaLink opens in a new tab.\" class=\"TextLink_text-link__dBSS0 TextLink_enabled__dJF3l\" href=\"https:\/\/www.mirror.co.uk\/news\/health\/dementia-risk-can-halved-simple-37600744\" rel=\"follow nofollow noopener\" tabindex=\"0\" target=\"_blank\">dementia<\/a>.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh\" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">About 1600 healthy adults aged 55-80 will be recruited at research sites around the world under the phase III PrevenTRON study.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh\" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">Surrey and Borders Partnership <a aria-label=\"\" class=\"TextLink_text-link__dBSS0 TextLink_enabled__dJF3l\" href=\"https:\/\/www.mirror.co.uk\/all-about\/nhs\" rel=\"follow nofollow noopener\" tabindex=\"0\" target=\"\">NHS<\/a> Foundation Trust became the first healthcare body in Europe to launch the trial this week &#8211; and will be able to recruit participants from across the UK<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh\" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">The trial is sponsored and run globally by the Swiss pharmaceutical company Roche, with Professor Ramin Nilforooshan from the NHS trust acting as chief investigator for the whole continent.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh\" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">He said: \u201cBeing the first site across Europe and the third in the world to open PrevenTRON is a proud moment for our Research and Development team and for the communities we serve.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh\" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">\u201cFor decades, research has focused on treating Alzheimer\u2019s disease after symptoms appear. PrevenTRON addresses a different question, whether we can act earlier, before symptoms begin.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh\" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">\u201cThrough research and trials like PrevenTRON, we are very excited for the potential to help millions of people affected by Alzheimer\u2019s disease.\u201d<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh\" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">Alzheimer\u2019s disease is the most common form of dementia, making up 60 to 80% of the one million dementia cases in the UK.<\/p>\n<p>What are the symptoms of Alzheimer&#8217;s?<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh\" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">According to the NHS, symptoms of Alzheimer&#8217;s disease often progress slowly, over several years.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh\" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">Unexplained lapses in memory typically appear at the first stage of the illness, such as:<\/p>\n<p>Forgetting recent conversations or eventsMisplacing itemsForgetting the names of places and objectsHaving trouble thinking of the right wordAsking questions repetitivelyShowing poor judgement or finding it harder to make decisionsBecoming more reluctant to try new things<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh\" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">By the middle stage, people with Alzheimer&#8217;s may struggle to remember the names of family or friends, or may not recognise them.<\/p>\n","protected":false},"excerpt":{"rendered":"A groundbreaking trial will see healthy adults across Britain with no signs of memory loss given an Alzheimer&#8217;s&hellip;\n","protected":false},"author":2,"featured_media":762227,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[43],"tags":[854,102,2960,56,54,55],"class_list":["post-762226","post","type-post","status-publish","format-standard","has-post-thumbnail","category-healthcare","tag-dementia","tag-health","tag-healthcare","tag-uk","tag-united-kingdom","tag-unitedkingdom"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/762226","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/comments?post=762226"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/762226\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media\/762227"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media?parent=762226"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/categories?post=762226"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/tags?post=762226"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}