{"id":77395,"date":"2025-08-19T09:07:09","date_gmt":"2025-08-19T09:07:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/uk\/77395\/"},"modified":"2025-08-19T09:07:09","modified_gmt":"2025-08-19T09:07:09","slug":"multidrug-therapy-could-help-both-the-heart-and-the-brain","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/uk\/77395\/","title":{"rendered":"Multidrug Therapy Could Help Both the Heart and the Brain"},"content":{"rendered":"<p>A groundbreaking analysis reveals that older adults taking a combination of medications for high blood pressure, cholesterol, and diabetes showed slower cognitive decline compared to those taking fewer medications.<\/p>\n<p>The impact is significant. The cognitive benefits were equivalent to being 3 years younger than the average age in the study sample.<\/p>\n<p>The research tracked over 4600 older adults without dementia, documenting their medication use and cognitive function over approximately 9 years. The findings were remarkable: Those taking all three medication classes showed notably slower decline in global cognition, particularly in semantic and working memory.<\/p>\n<p>In a deeper analysis of nearly 1900 deceased participants, those who had been taking the combination therapy showed significantly lower odds of various brain pathologies, including reduced <a href=\"https:\/\/emedicine.medscape.com\/article\/463147-overview\" class=\"cl_ref_article\" rel=\"nofollow noopener\" target=\"_blank\">atherosclerosis<\/a> and less global <a href=\"https:\/\/emedicine.medscape.com\/article\/1134817-overview\" class=\"cl_ref_article\" rel=\"nofollow noopener\" target=\"_blank\">Alzheimer&#8217;s disease<\/a> pathology.<\/p>\n<p>While these results are promising, researchers emphasize that additional studies are needed before making definitive clinical recommendations.<\/p>\n<p>This content was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.<\/p>\n","protected":false},"excerpt":{"rendered":"A groundbreaking analysis reveals that older adults taking a combination of medications for high blood pressure, cholesterol, and&hellip;\n","protected":false},"author":2,"featured_media":77396,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42],"tags":[21263,19697,19698,15043,7341,39493,861,866,862,860,102,9778,39494,19695,6591,39492,863,865,864,56,54,55],"class_list":["post-77395","post","type-post","status-publish","format-standard","has-post-thumbnail","category-medication","tag-alzheimer-disease-alzheimers-disease-alzheimers","tag-atherosclerosis","tag-atherosclerotic-disease-of-the-carotid-artery","tag-blood","tag-brain","tag-combination-drug-therapy","tag-elder-care","tag-elderly","tag-geriatric-medicine","tag-geriatrics","tag-health","tag-heart","tag-increased-blood-pressure","tag-lipids-lipids-management","tag-medication","tag-mild-cognitive-impairment-minimal-cognitive-impairment-mci-mild-cognitive-impairment-mci","tag-older-adults","tag-senior-citizens","tag-seniors","tag-uk","tag-united-kingdom","tag-unitedkingdom"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/77395","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/comments?post=77395"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/77395\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media\/77396"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media?parent=77395"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/categories?post=77395"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/tags?post=77395"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}