{"id":797291,"date":"2026-10-09T18:46:36","date_gmt":"2026-10-09T18:46:36","guid":{"rendered":"https:\/\/www.newsbeep.com\/uk\/797291\/"},"modified":"2026-10-09T18:46:36","modified_gmt":"2026-10-09T18:46:36","slug":"drugs-like-ozempic-and-wegovy-are-linked-to-a-lower-risk-of-alzheimers-disease-new-study-says","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/uk\/797291\/","title":{"rendered":"Drugs like Ozempic and Wegovy are linked to a lower risk of Alzheimer\u2019s disease, new study says"},"content":{"rendered":"<p class=\"mb-4 text-lg md:leading-8 break-words\">Semaglutide\u2014the <a data-ylk=\"slk:diabetes;elm:context_link;itc:0;sec:content-canvas;\" data-yga=\"{&quot;yLinkElement&quot;:&quot;link&quot;,&quot;yLinkElementType&quot;:&quot;article_link&quot;}\" href=\"https:\/\/fortune.com\/well\/article\/diabetes-prediabetes-obesity-half-united-states-population-insulin-wegovy-type1-type2-signs-symptoms\/\" rel=\"noopener nofollow\" target=\"_blank\">diabetes<\/a> and <a data-ylk=\"slk:weight-loss;elm:context_link;itc:0;sec:content-canvas;\" data-yga=\"{&quot;yLinkElement&quot;:&quot;link&quot;,&quot;yLinkElementType&quot;:&quot;article_link&quot;}\" href=\"https:\/\/fortune.com\/well\/article\/weight-loss-myths-diet-exercise-glp1-medication\/?utm_source=search&amp;utm_medium=advanced_search&amp;utm_campaign=search_link_clicks\" rel=\"noopener nofollow\" target=\"_blank\">weight-loss<\/a> drug known by brand names like <a data-ylk=\"slk:Ozempic;elm:context_link;itc:0;sec:content-canvas;\" data-yga=\"{&quot;yLinkElement&quot;:&quot;link&quot;,&quot;yLinkElementType&quot;:&quot;article_link&quot;}\" href=\"https:\/\/fortune.com\/well\/2024\/09\/11\/ozempic-maker-weight-loss-pill\/\" rel=\"noopener nofollow\" target=\"_blank\">Ozempic<\/a> and <a data-ylk=\"slk:Wegovy;elm:context_link;itc:0;sec:content-canvas;\" data-yga=\"{&quot;yLinkElement&quot;:&quot;link&quot;,&quot;yLinkElementType&quot;:&quot;article_link&quot;}\" href=\"https:\/\/fortune.com\/well\/article\/weight-loss-drug-glp1-ozempic-wegovy-zepbound-vs-diet\/?utm_source=search&amp;utm_medium=suggested_search&amp;utm_campaign=search_link_clicks\" rel=\"noopener nofollow\" target=\"_blank\">Wegovy<\/a>\u2014is continuing to show its potential to treat a wide range of other conditions.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">While recent studies have revealed that these drugs may help stop <a data-ylk=\"slk:opioid addiction;elm:context_link;itc:0;sec:content-canvas;\" data-yga=\"{&quot;yLinkElement&quot;:&quot;link&quot;,&quot;yLinkElementType&quot;:&quot;article_link&quot;}\" href=\"https:\/\/fortune.com\/2024\/09\/25\/ozempic-wegovy-novo-nordisk-opioid-addiction-study\/?utm_source=search&amp;utm_medium=suggested_search&amp;utm_campaign=search_link_clicks\" rel=\"noopener nofollow\" target=\"_blank\">opioid addiction<\/a>, <a data-ylk=\"slk:smoking;elm:context_link;itc:0;sec:content-canvas;\" data-yga=\"{&quot;yLinkElement&quot;:&quot;link&quot;,&quot;yLinkElementType&quot;:&quot;article_link&quot;}\" href=\"https:\/\/www.acpjournals.org\/doi\/10.7326\/M23-2718#:~:text=Semaglutide%20was%20associated%20with%20reduced,30%20days%20of%20prescription%20initiation.\" rel=\"noopener nofollow\" target=\"_blank\">smoking<\/a>, and even help people <a data-ylk=\"slk:live longer;elm:context_link;itc:0;sec:content-canvas;\" data-yga=\"{&quot;yLinkElement&quot;:&quot;link&quot;,&quot;yLinkElementType&quot;:&quot;article_link&quot;}\" href=\"https:\/\/fortune.com\/well\/article\/ozempic-glp1-help-people-live-longer-longevity\/?utm_source=search&amp;utm_medium=suggested_search&amp;utm_campaign=search_link_clicks\" rel=\"noopener nofollow\" target=\"_blank\">live longer<\/a>, a new study published in the journal <a data-ylk=\"slk:Alzheimer&#039;s &amp; Dementia: The Journal of the Alzheimer&#039;s Association;elm:context_link;itc:0;sec:content-canvas;\" data-yga=\"{&quot;yLinkElement&quot;:&quot;link&quot;,&quot;yLinkElementType&quot;:&quot;article_link&quot;}\" href=\"https:\/\/doi.org\/10.1002\/alz.14313\" rel=\"noopener nofollow\" target=\"_blank\">Alzheimer&#8217;s &amp; Dementia: The Journal of the Alzheimer&#8217;s Association<\/a> now also links semaglutide to a decreased risk of Alzheimer&#8217;s disease.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">In the study, researchers at Case Western Reserve School of Medicine analyzed three years of electronic records of nearly one million Americans with type 2 diabetes. They compared patients using <a data-ylk=\"slk:semaglutide programs;elm:context_link;itc:0;sec:content-canvas;\" data-yga=\"{&quot;yLinkElement&quot;:&quot;link&quot;,&quot;yLinkElementType&quot;:&quot;article_link&quot;}\" href=\"https:\/\/fortune.com\/article\/best-online-semaglutide-programs\/\" rel=\"noopener nofollow\" target=\"_blank\">semaglutide programs<\/a>\u2014a glucagon-like peptide-1 (<a data-ylk=\"slk:GLP-1;elm:context_link;itc:0;sec:content-canvas;\" data-yga=\"{&quot;yLinkElement&quot;:&quot;link&quot;,&quot;yLinkElementType&quot;:&quot;article_link&quot;}\" href=\"https:\/\/fortune.com\/well\/article\/weight-loss-drug-glp1-ozempic-wegovy-zepbound-vs-diet\/\" rel=\"noopener nofollow\" target=\"_blank\">GLP-1<\/a>) receptor agonist\u2014to those prescribed one of seven other anti-diabetic drugs, including metformin, dipeptidyl-peptidase-4 inhibitors (DPP-4i), and other GLP-1RAs (which mimic the effects of GLP-1s). Patients prescribed semaglutide had a 40% to 70% reduced risk of first-time Alzheimer&#8217;s diagnosis, compared to other antidiabetic medications.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;The result is what we expected,&#8221; Rong Xu, biomedical informatics professor at Case Western Reserve University and lead researcher on the study, tells Fortune.\u00a0<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Given other studies that show semaglutide can help\u00a0<a data-ylk=\"slk:reduce inflammation;elm:context_link;itc:0;sec:content-canvas;\" data-yga=\"{&quot;yLinkElement&quot;:&quot;link&quot;,&quot;yLinkElementType&quot;:&quot;article_link&quot;}\" href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10992717\/#:~:text=In%20a%20study%20involving%2040,of%20cardiovascular%20disorders%20%5B63%5D.\" rel=\"noopener nofollow\" target=\"_blank\">reduce inflammation<\/a>\u00a0in the body,\u00a0<a data-ylk=\"slk:prevent neuron damage;elm:context_link;itc:0;sec:content-canvas;\" data-yga=\"{&quot;yLinkElement&quot;:&quot;link&quot;,&quot;yLinkElementType&quot;:&quot;article_link&quot;}\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30741689\/\" rel=\"noopener nofollow\" target=\"_blank\">prevent neuron damage<\/a>, promote\u00a0<a data-ylk=\"slk:weight loss;elm:context_link;itc:0;sec:content-canvas;\" data-yga=\"{&quot;yLinkElement&quot;:&quot;link&quot;,&quot;yLinkElementType&quot;:&quot;article_link&quot;}\" href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2032183\" rel=\"noopener nofollow\" target=\"_blank\">weight loss<\/a>, control\u00a0<a data-ylk=\"slk:diabetes;elm:context_link;itc:0;sec:content-canvas;\" data-yga=\"{&quot;yLinkElement&quot;:&quot;link&quot;,&quot;yLinkElementType&quot;:&quot;article_link&quot;}\" href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6231279\/\" rel=\"noopener nofollow\" target=\"_blank\">diabetes<\/a>, and prevent\u00a0<a data-ylk=\"slk:cardiovascular disease;elm:context_link;itc:0;sec:content-canvas;\" data-yga=\"{&quot;yLinkElement&quot;:&quot;link&quot;,&quot;yLinkElementType&quot;:&quot;article_link&quot;}\" href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2307563\" rel=\"noopener nofollow\" target=\"_blank\">cardiovascular disease<\/a>\u2014in addition to helping curb the urge to smoke and drink\u2014Xu says the drug is already lowering risk factors for Alzheimer&#8217;s.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;If we can target these risk factors\u2026semaglutide can be beneficial in preventing or slowing down Alzheimer&#8217;s disease symptoms or development,&#8221; Xu says.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Xu makes it clear that this study wasn&#8217;t meant to examine whether semaglutide lowers the risk for Alzheimer&#8217;s in people without diabetes.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;Diabetes itself is a risk factor [for Alzheimer&#8217;s],&#8221; she says. Because of that, Xu and her team wanted to see if people at heightened risk\u2014those who have diabetes\u2014would have better outcomes with semaglutide versus other diabetes medications.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Researchers can&#8217;t say that semaglutide does lower Alzheimer&#8217;s risk, only that there is a link. More research is needed.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">But Xu is also optimistic for what these study findings might mean for people currently diagnosed with Alzheimer&#8217;s. She&#8217;d like to see if semaglutide could improve outcomes or have a therapeutic effect on those currently managing Alzheimer&#8217;s symptoms.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">A version of this story was published on Fortune.com on Oct. 24, 2024.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">For more on Alzheimer&#8217;s:<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">This story was originally featured on <a data-ylk=\"slk:Fortune.com;elm:context_link;itc:0;sec:content-canvas;\" data-yga=\"{&quot;yLinkElement&quot;:&quot;link&quot;,&quot;yLinkElementType&quot;:&quot;article_link&quot;}\" href=\"https:\/\/fortune.com\/well\/article\/diabetes-weight-loss-drugs-ozempic-wegovy-lower-risk-alzheimers-disease\/\" rel=\"noopener nofollow\" target=\"_blank\">Fortune.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"Semaglutide\u2014the diabetes and weight-loss drug known by brand names like Ozempic and Wegovy\u2014is continuing to show its potential&hellip;\n","protected":false},"author":2,"featured_media":797292,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42],"tags":[915,262146,102,6591,262145,16839,15037,56,54,55],"class_list":["post-797291","post","type-post","status-publish","format-standard","has-post-thumbnail","category-medication","tag-alzheimers-disease","tag-alzheimers-diagnosis","tag-health","tag-medication","tag-rong-xu","tag-semaglutide","tag-type-2-diabetes","tag-uk","tag-united-kingdom","tag-unitedkingdom"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/797291","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/comments?post=797291"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/posts\/797291\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media\/797292"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/media?parent=797291"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/categories?post=797291"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/uk\/wp-json\/wp\/v2\/tags?post=797291"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}