{"id":828699,"date":"2026-11-09T03:46:16","date_gmt":"2026-11-09T03:46:16","guid":{"rendered":"https:\/\/www.newsbeep.com\/uk\/828699\/"},"modified":"2026-11-09T03:46:16","modified_gmt":"2026-11-09T03:46:16","slug":"heart-drug-flops-raise-doubts-about-high-tech-approaches-to-pharma","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/uk\/828699\/","title":{"rendered":"Heart drug flops raise doubts about high-tech approaches to pharma"},"content":{"rendered":"

The next time someone tells you that artificial intelligence<\/a>, or any other new technology, is going to cure every disease<\/a>, point them to the effort to fight heart attacks and strokes, which together are the largest killer in the developed world.<\/p>\n

Because again and again, pharmaceutical researchers have learned the same hard lesson: Technologies that were supposed to speed new medicines to patients have fallen short. Two studies presented Saturday at the annual meeting of the American Heart Association are a perfect example. A new understanding of genetics was supposed to increase the odds of success \u2014 and did anything but.<\/p>\n

One study showed that a Novartis drug, pelacarsen<\/a>, had no effect on the rate of heart attacks and strokes despite lowering a substance in the blood called Lp(a), which genetics said should\u00a0reduce cardiovascular risk. Another large study, from Novo Nordisk, of an anti-inflammatory targeting a protein called IL-6 also showed no benefit<\/a>.\u00a0<\/p>\n

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